› 2xqv

X-ray diffraction
1.93Å resolution

The X-ray structure of the Zn(II) bound ZnuA from Salmonella enterica

Released:
DOI: 10.2210/pdb2xqv/pdb
PDB entry 2xqv coloured by chain, front view.
PDB entry 2xqv coloured by chain, side view.
PDB entry 2xqv coloured by chain, top view.
Source organism: Salmonella enterica subsp. enterica serovar Typhimurium
Primary publication:
The X-ray structure of the zinc transporter ZnuA from Salmonella enterica discloses a unique triad of zinc-coordinating histidines.
Ilari A, Alaleona F, Petrarca P, Battistoni A, Chiancone E
J Mol Biol 409 630-41 (2011)
PMID: 21530543

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-187320 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
High-affinity zinc uptake system protein ZnuA Chain: A
Molecule details ›
Chain: A
Length: 288 amino acids
Theoretical weight: 31.59 KDa
Source organism: Salmonella enterica subsp. enterica serovar Typhimurium
Expression system: Escherichia coli DH5[alpha]
UniProt:
  • Canonical: Q8ZNV8 (Residues: 46-333; Coverage: 100%)
Gene names: STM1891, znuA
Sequence domains: Zinc-uptake complex component A periplasmic
Structure domains: Nitrogenase molybdenum iron protein domain

Ligands and Environments

2 bound ligands:
Ligand ZN 1 x ZN
Ligand SO4 2 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.1
Spacegroup: P63
Unit cell:
a: 141.68Å b: 141.68Å c: 30.858Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.207 0.206 0.228
Expression system: Escherichia coli DH5[alpha]

Quick links

Citations

5 review citations

Metal limitation and toxicity at the interface between host and pathogen.
Becker et al. (2014)
4 more

2 mentions without citation

Manganese uptake and streptococcal virulence.
Eijkelkamp et al. (2015)
1 more