Family

High-affinity zinc uptake system protein ZnuA (IPR035520)

Short name: ZnuA

Overlapping homologous superfamilies

None.

Family relationships

Description

Zinc binding proteins ZnuA have been shown to function as initial receptors in the ABC uptake of Zn2+. They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct fold and ligand binding mechanism. They are comprised of two globular subdomains connected by a single helix and bind their specific ligands in the cleft between these domains. A typical TroA protein is comprised of two globular subdomains connected by a single helix and can bind the metal ion in the cleft between these domains. In addition, these proteins sometimes have a low complexity region containing a metal-binding histidine-rich motif (repetitive HDH sequence) [PMID: 11506909, PMID: 9680209, PMID: 11421271, PMID: 11831459].

GO terms

Biological Process

GO:0006829 zinc ion transport

Molecular Function

GO:0046872 metal ion binding

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
CDD