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Yersinia Pestis Plasminogen Activator Pla

Source organism: Yersinia pestis
Biochemical function: aspartic-type endopeptidase activity
Biological process: proteolysis
Cellular component: cell outer membrane

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EC 3.4.23.48: Plasminogen activator Pla

Reaction catalysed:
Converts human Glu-plasminogen to plasmin by cleaving the 560-Arg-|-Val-561 peptide bond that is also hydrolyzed by the mammalian u-plasminogen activator and t-plasminogen activator. Also cleaves arginyl bonds in other proteins.
Systematic name:
-
Alternative Name(s):
  • Coagulase/fibrinolysin

GO terms

Biochemical function:
Biological process:
Cellular component:

Sequence family

Pfam Protein family (Pfam)
PF01278
Domain description: Omptin family
Occurring in:
  1. Plasminogen activator
The deposited structure of PDB entry 2x4m contains 4 copies of Pfam domain PF01278 (Omptin family) in Plasminogen activator. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR000036
Domain description: Peptidase A26, omptin
Occurring in:
  1. Plasminogen activator
IPR020079
Domain description: Peptidase A26, omptin, conserved site
Occurring in:
  1. Plasminogen activator
IPR020080
Domain description: Outer membrane adhesin/peptidase omptin
Occurring in:
  1. Plasminogen activator

Structure domain

CATH CATH domain
2.40.128.90
Class: Mainly Beta
Architecture: Beta Barrel
Topology: Lipocalin
Homology: OMPT-like
Occurring in:
  1. Plasminogen activator
The deposited structure of PDB entry 2x4m contains 4 copies of CATH domain 2.40.128.90 (Lipocalin) in Plasminogen activator. Showing 1 copy in chain A.

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