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Crystal srtucture of the binary complex between ferredoxin and ferredoxin:thioredoxin reductase

Source organism: Synechocystis sp.
Biochemical function: protein binding
Biological process: photosynthesis
Cellular component: not assigned

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EC 1.8.7.2: Ferredoxin:thioredoxin reductase

Reaction catalysed:
2 reduced ferredoxin + thioredoxin disulfide = 2 oxidized ferredoxin + thioredoxin + 2 H(+)
Systematic name:
Ferredoxin:thioredoxin disulfide oxidoreductase

GO terms

Biochemical function:
Biological process:
Cellular component:
  • not assigned

Sequence families

Pfam Protein families (Pfam)
PF00111
Domain description: 2Fe-2S iron-sulfur cluster binding domain
Occurring in:
  1. Ferredoxin-1
The deposited structure of PDB entry 2pvg contains 1 copy of Pfam domain PF00111 (2Fe-2S iron-sulfur cluster binding domain) in Ferredoxin-1. Showing 1 copy in chain C.

PF02941
Domain description: Ferredoxin thioredoxin reductase variable alpha chain
Occurring in:
  1. Ferredoxin-thioredoxin reductase, variable chain
The deposited structure of PDB entry 2pvg contains 1 copy of Pfam domain PF02941 (Ferredoxin thioredoxin reductase variable alpha chain) in Ferredoxin-thioredoxin reductase, variable chain. Showing 1 copy in chain B.

PF02943
Domain description: Ferredoxin thioredoxin reductase catalytic beta chain
Occurring in:
  1. Ferredoxin-thioredoxin reductase, catalytic chain
The deposited structure of PDB entry 2pvg contains 1 copy of Pfam domain PF02943 (Ferredoxin thioredoxin reductase catalytic beta chain) in Ferredoxin-thioredoxin reductase, catalytic chain. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR001041
Domain description: 2Fe-2S ferredoxin-type iron-sulfur binding domain
Occurring in:
  1. Ferredoxin-1
IPR004209
Domain description: Ferredoxin thioredoxin reductase catalytic beta subunit
Occurring in:
  1. Ferredoxin-thioredoxin reductase, catalytic chain
IPR036644
Domain description: Ferredoxin thioredoxin reductase catalytic beta subunit superfamily
Occurring in:
  1. Ferredoxin-thioredoxin reductase, catalytic chain
IPR006058
Domain description: 2Fe-2S ferredoxin, iron-sulphur binding site
Occurring in:
  1. Ferredoxin-1
IPR036010
Domain description: 2Fe-2S ferredoxin-like superfamily
Occurring in:
  1. Ferredoxin-1
IPR012675
Domain description: Beta-grasp domain superfamily
Occurring in:
  1. Ferredoxin-1
IPR010241
Domain description: Ferredoxin [2Fe-2S], plant
Occurring in:
  1. Ferredoxin-1
IPR004207
Domain description: Ferredoxin thioredoxin reductase, alpha chain
Occurring in:
  1. Ferredoxin-thioredoxin reductase, variable chain
IPR044166
Domain description: Ferredoxin-thioredoxin reductase, variable chain
Occurring in:
  1. Ferredoxin-thioredoxin reductase, variable chain
IPR008990
Domain description: Electron transport accessory-like domain superfamily
Occurring in:
  1. Ferredoxin-thioredoxin reductase, variable chain
IPR024707
Domain description: Ferredoxin-thioredoxin reductase catalytic subunit, cyanobacteria-type
Occurring in:
  1. Ferredoxin-thioredoxin reductase, catalytic chain

Structure domains

CATH CATH domains
3.10.20.30
Class: Alpha Beta
Architecture: Roll
Topology: Ubiquitin-like (UB roll)
Homology: Ubiquitin-like (UB roll)
Occurring in:
  1. Ferredoxin-1
The deposited structure of PDB entry 2pvg contains 1 copy of CATH domain 3.10.20.30 (Ubiquitin-like (UB roll)) in Ferredoxin-1. Showing 1 copy in chain C.
2.30.30.50
Class: Mainly Beta
Architecture: Roll
Topology: SH3 type barrels.
Homology: SH3 type barrels.
Occurring in:
  1. Ferredoxin-thioredoxin reductase, variable chain
The deposited structure of PDB entry 2pvg contains 1 copy of CATH domain 2.30.30.50 (SH3 type barrels.) in Ferredoxin-thioredoxin reductase, variable chain. Showing 1 copy in chain B.
3.90.460.10
Class: Alpha Beta
Architecture: Alpha-Beta Complex
Topology: Ferredoxin Thioredoxin Reductase
Homology: Ferredoxin thioredoxin reductase catalytic beta subunit
Occurring in:
  1. Ferredoxin-thioredoxin reductase, catalytic chain
The deposited structure of PDB entry 2pvg contains 1 copy of CATH domain 3.90.460.10 (Ferredoxin Thioredoxin Reductase) in Ferredoxin-thioredoxin reductase, catalytic chain. Showing 1 copy in chain A.

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