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Structure of the PR domain from PRDM16

Source organism: Homo sapiens
Biochemical function: histone H3K9 methyltransferase activity
Biological process: not assigned
Cellular component: not assigned

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EC 2.1.1.367: [Histone H3]-lysine(9) N-methyltransferase

Reaction catalysed:
S-adenosyl-L-methionine + a [histone H3]-L-lysine(9) = S-adenosyl-L-homocysteine + a [histone H3]-N(6)-methyl-L-lysine(9)
Systematic name:
S-adenosyl-L-methionine:[histone H3]-L-lysine(9) N(6)-methyltransferase

GO terms

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence family

Pfam Protein family (Pfam)
PF21549
Domain description: PR domain zinc finger protein 2, PR domain
Occurring in:
  1. Histone-lysine N-methyltransferase PRDM16
The deposited structure of PDB entry 2n1i contains 1 copy of Pfam domain PF21549 (PR domain zinc finger protein 2, PR domain) in Histone-lysine N-methyltransferase PRDM16. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR001214
Domain description: SET domain
Occurring in:
  1. Histone-lysine N-methyltransferase PRDM16
IPR046341
Domain description: SET domain superfamily
Occurring in:
  1. Histone-lysine N-methyltransferase PRDM16
IPR044410
Domain description: PRDM16, PR/SET domain
Occurring in:
  1. Histone-lysine N-methyltransferase PRDM16

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