› › Structure analysis

Insulin receptor (domains 1-3)

X-ray diffraction
2.32Å resolution
PDB entry 2hr7 coloured by chain, front view.
PDB entry 2hr7 coloured by chain, side view.
PDB entry 2hr7 coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
homo dimer (preferred)
Entry contents: 1 distinct polypeptide molecule

Quick links

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Assembly Name: Insulin receptor subunit beta
hide full assembly name
Multimeric state: homo dimer
Accessible surface area: 48157.27 Å2
Buried surface area: 21207.48 Å2
Dissociation area: 2,240.61 Å2
Dissociation energy (ΔGdiss): 4.42 kcal/mol
Dissociation entropy (TΔSdiss): 15.23 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-138939

Macromolecules

Insulin receptor subunit alpha
Chains: A, B
Length: 486 amino acids
Theoretical weight: 55.54 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt:
  • Canonical: P06213 (Residues: 28-512; Coverage: 36%)
Gene name: INSR
Pfam:
InterPro:
CATH:
Insulin receptor subunit alpha in PDB entry 2hr7, assembly 1, front view.
Insulin receptor subunit alpha in PDB entry 2hr7, assembly 1, side view.
Insulin receptor subunit alpha in PDB entry 2hr7, assembly 1, top view.
Molecule details ›

Search similar proteins

Quick links