2g46

Solution NMR

structure of vSET in complex with meK27 H3 Pept. and cofactor product SAH

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
PDBe Complex ID:
PDB-CPX-127666 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
SET domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 119 amino acids
Theoretical weight: 13.61 KDa
Source organism: Paramecium bursaria Chlorella virus 1
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O41094 (Residues: 1-119; Coverage: 100%)
Gene name: A612L
Sequence domains: SET domain
Structure domains: SET domain
Histone H3 Chains: C, D
Molecule details ›
Chains: C, D
Length: 21 amino acids
Theoretical weight: 2.13 KDa
Source organism: Nicotiana tabacum
Expression system: Not provided
UniProt:
  • Canonical: O24165 (Residues: 14-34; Coverage: 55%)

Ligands and Environments

1 bound ligand:
1 modified residue:

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing torsion angle dynamics
Expression systems:
  • Escherichia coli BL21(DE3)
  • Not provided