Function and Biology

NMR studies on the interaction of Insulin-Growth Factor II (IGF-II) with IGF2R domain 11

Source organism: Homo sapiens
Biochemical function: signaling receptor activity
Biological process: lysosomal transport
Cellular component: not assigned

GO terms

Biochemical function:
Biological process:
Cellular component:
  • not assigned

Sequence family

Pfam Protein family (Pfam)
PF00878
Domain description: Cation-independent mannose-6-phosphate receptor repeat
Occurring in:
  1. Cation-independent mannose-6-phosphate receptor
The deposited structure of PDB entry 2cnj contains 2 copies of Pfam domain PF00878 (Cation-independent mannose-6-phosphate receptor repeat) in Cation-independent mannose-6-phosphate receptor. Showing 2 copies in chain A [auth D].

InterPro InterPro annotations
IPR000479
Domain description: Cation-independent mannose-6-phosphate receptor repeat
Occurring in:
  1. Cation-independent mannose-6-phosphate receptor
IPR009011
Domain description: Mannose-6-phosphate receptor binding domain superfamily
Occurring in:
  1. Cation-independent mannose-6-phosphate receptor
IPR044865
Domain description: MRH domain
Occurring in:
  1. Cation-independent mannose-6-phosphate receptor

Structure domain

CATH CATH domain
2.70.130.10
Class: Mainly Beta
Architecture: Distorted Sandwich
Topology: Cation-dependent Mannose-6-phosphate Receptor; Chain A
Homology: Mannose-6-phosphate receptor binding domain
Occurring in:
  1. Cation-independent mannose-6-phosphate receptor
The deposited structure of PDB entry 2cnj contains 1 copy of CATH domain 2.70.130.10 (Cation-dependent Mannose-6-phosphate Receptor; Chain A) in Cation-independent mannose-6-phosphate receptor. Showing 1 copy in chain A [auth D].
SCOP SCOP annotation
50912
Class: All beta proteins
Fold: Mannose 6-phosphate receptor domain
Superfamily: Mannose 6-phosphate receptor domain
Occurring in:
  1. Cation-independent mannose-6-phosphate receptor
The deposited structure of PDB entry 2cnj contains 1 copy of SCOP domain 50912 (Mannose 6-phosphate receptor domain) in Cation-independent mannose-6-phosphate receptor. Showing 1 copy in chain A [auth D].