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structure of human UAP56 in complex with ADP

X-ray diffraction
2.7Å resolution
PDB entry 1xtj coloured by chain, front view.
PDB entry 1xtj coloured by chain, side view.
PDB entry 1xtj coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Spliceosome RNA helicase DDX39B
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Multimeric state: monomeric
Accessible surface area: 19413.79 Å2
Buried surface area: 769.12 Å2
Dissociation area: 76.86 Å2
Dissociation energy (ΔGdiss): 12.79 kcal/mol
Dissociation entropy (TΔSdiss): -1.46 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-171824

Macromolecules

Spliceosome RNA helicase DDX39B
Chain: A
Length: 386 amino acids
Theoretical weight: 44.44 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q13838 (Residues: 44-423; Coverage: 89%)
Gene names: BAT1, DDX39B, UAP56
Pfam:
InterPro:
CATH: P-loop containing nucleotide triphosphate hydrolases
SCOP: Tandem AAA-ATPase domain
Spliceosome RNA helicase DDX39B in PDB entry 1xtj, assembly 1, front view.
Spliceosome RNA helicase DDX39B in PDB entry 1xtj, assembly 1, side view.
Spliceosome RNA helicase DDX39B in PDB entry 1xtj, assembly 1, top view.
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