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CRYSTAL STRUCTURE OF AN INTEGRIN BETA3-TALIN CHIMERA

Source organisms:
Biochemical function: not assigned
Biological process: not assigned
Cellular component: cytoskeleton

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GO terms

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:

Sequence family

Pfam Protein family (Pfam)
PF00373
Domain description: FERM central domain
Occurring in:
  1. Talin-1
The deposited structure of PDB entry 1mk7 contains 2 copies of Pfam domain PF00373 (FERM central domain) in Talin-1. Showing 1 copy in chain B.

InterPro InterPro annotations
IPR019748
Domain description: FERM central domain
Occurring in:
  1. Talin-1
IPR002404
Domain description: IRS-type PTB domain
Occurring in:
  1. Talin-1
IPR011993
Domain description: PH-like domain superfamily
Occurring in:
  1. Talin-1
IPR019747
Domain description: FERM conserved site
Occurring in:
  1. Talin-1
IPR035963
Domain description: FERM superfamily, second domain
Occurring in:
  1. Talin-1
IPR014352
Domain description: FERM/acyl-CoA-binding protein superfamily
Occurring in:
  1. Talin-1
IPR000299
Domain description: FERM domain
Occurring in:
  1. Talin-1

Structure domains

CATH CATH domains
2.30.29.30
Class: Mainly Beta
Architecture: Roll
Topology: PH-domain like
Homology: Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
Occurring in:
  1. Talin-1
The deposited structure of PDB entry 1mk7 contains 2 copies of CATH domain 2.30.29.30 (PH-domain like) in Talin-1. Showing 1 copy in chain B.
1.20.80.10
Class: Mainly Alpha
Architecture: Up-down Bundle
Topology: Acyl-CoA Binding Protein
Homology: Acyl-CoA Binding Protein
Occurring in:
  1. Talin-1
The deposited structure of PDB entry 1mk7 contains 2 copies of CATH domain 1.20.80.10 (Acyl-CoA Binding Protein) in Talin-1. Showing 1 copy in chain B.
SCOP SCOP annotations
50776
Class: All beta proteins
Fold: PH domain-like barrel
Superfamily: PH domain-like
Occurring in:
  1. Talin-1
The deposited structure of PDB entry 1mk7 contains 2 copies of SCOP domain 50776 (Third domain of FERM) in Talin-1. Showing 1 copy in chain B.
47032
Class: All alpha proteins
Fold: Acyl-CoA binding protein-like
Superfamily: Second domain of FERM
Occurring in:
  1. Talin-1
The deposited structure of PDB entry 1mk7 contains 2 copies of SCOP domain 47032 (Second domain of FERM) in Talin-1. Showing 1 copy in chain B.

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