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THE CRYSTAL STRUCTURE OF ELONGATION FACTOR EF-TU FROM THERMUS AQUATICUS IN THE GTP CONFORMATION

Source organism: Thermus aquaticus
Biochemical function: GTP binding
Biological process: translational elongation
Cellular component: cytosol

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GO terms

Sequence families

Pfam Protein families (Pfam)
PF03143
Domain description: Elongation factor Tu C-terminal domain
Occurring in:
  1. Elongation factor Tu
The deposited structure of PDB entry 1eft contains 1 copy of Pfam domain PF03143 (Elongation factor Tu C-terminal domain) in Elongation factor Tu. Showing 1 copy in chain A.

PF03144
Domain description: Elongation factor Tu domain 2
Occurring in:
  1. Elongation factor Tu
The deposited structure of PDB entry 1eft contains 1 copy of Pfam domain PF03144 (Elongation factor Tu domain 2) in Elongation factor Tu. Showing 1 copy in chain A.

PF00009
Domain description: Elongation factor Tu GTP binding domain
Occurring in:
  1. Elongation factor Tu
The deposited structure of PDB entry 1eft contains 1 copy of Pfam domain PF00009 (Elongation factor Tu GTP binding domain) in Elongation factor Tu. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR000795
Domain description: Translational (tr)-type GTP-binding domain
Occurring in:
  1. Elongation factor Tu
IPR027417
Domain description: P-loop containing nucleoside triphosphate hydrolase
Occurring in:
  1. Elongation factor Tu
IPR009001
Domain description: Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal
Occurring in:
  1. Elongation factor Tu
IPR004160
Domain description: Translation elongation factor EFTu/EF1A, C-terminal
Occurring in:
  1. Elongation factor Tu
IPR004161
Domain description: Translation elongation factor EFTu-like, domain 2
Occurring in:
  1. Elongation factor Tu
IPR033720
Domain description: Elongation factor Tu, domain 2
Occurring in:
  1. Elongation factor Tu
IPR009000
Domain description: Translation protein, beta-barrel domain superfamily
Occurring in:
  1. Elongation factor Tu
IPR031157
Domain description: Tr-type G domain, conserved site
Occurring in:
  1. Elongation factor Tu
IPR005225
Domain description: Small GTP-binding protein domain
Occurring in:
  1. Elongation factor Tu
IPR041709
Domain description: Elongation factor Tu (EF-Tu), GTP-binding domain
Occurring in:
  1. Elongation factor Tu
IPR004541
Domain description: Translation elongation factor EFTu/EF1A, bacterial/organelle
Occurring in:
  1. Elongation factor Tu

Structure domains

CATH CATH domains
2.40.30.10
Class: Mainly Beta
Architecture: Beta Barrel
Topology: Elongation Factor Tu (Ef-tu); domain 3
Homology: Translation factors
Occurring in:
  1. Elongation factor Tu
The deposited structure of PDB entry 1eft contains 2 copies of CATH domain 2.40.30.10 (Elongation Factor Tu (Ef-tu); domain 3) in Elongation factor Tu. Showing 2 copies in chain A.
3.40.50.300
Class: Alpha Beta
Architecture: 3-Layer(aba) Sandwich
Topology: Rossmann fold
Homology: P-loop containing nucleotide triphosphate hydrolases
Occurring in:
  1. Elongation factor Tu
The deposited structure of PDB entry 1eft contains 1 copy of CATH domain 3.40.50.300 (Rossmann fold) in Elongation factor Tu. Showing 1 copy in chain A.
SCOP SCOP annotations
50466
Class: All beta proteins
Fold: Elongation factor/aminomethyltransferase common domain
Superfamily: EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
Occurring in:
  1. Elongation factor Tu
The deposited structure of PDB entry 1eft contains 1 copy of SCOP domain 50466 (EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain) in Elongation factor Tu. Showing 1 copy in chain A.
50448
Class: All beta proteins
Fold: Reductase/isomerase/elongation factor common domain
Superfamily: Translation proteins
Occurring in:
  1. Elongation factor Tu
The deposited structure of PDB entry 1eft contains 1 copy of SCOP domain 50448 (Elongation factors) in Elongation factor Tu. Showing 1 copy in chain A.
52592
Class: Alpha and beta proteins (a/b)
Fold: P-loop containing nucleoside triphosphate hydrolases
Superfamily: P-loop containing nucleoside triphosphate hydrolases
Occurring in:
  1. Elongation factor Tu
The deposited structure of PDB entry 1eft contains 1 copy of SCOP domain 52592 (G proteins) in Elongation factor Tu. Showing 1 copy in chain A.

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