› 1ggc

X-ray diffraction
2.8Å resolution

MAJOR ANTIGEN-INDUCED DOMAIN REARRANGEMENTS IN AN ANTIBODY

Released:
DOI: 10.2210/pdb1ggc/pdb
PDB entry 1ggc coloured by chain, front view.
PDB entry 1ggc coloured by chain, side view.
PDB entry 1ggc coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Major antigen-induced domain rearrangements in an antibody.
Stanfield RL, Takimoto-Kamimura M, Rini JM, Profy AT, Wilson IA
Structure 1 83-93 (1993)
PMID: 8069628

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-208649 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
IGG2A-KAPPA 50.1 FAB (LIGHT CHAIN) Chain: L
Molecule details ›
Chain: L
Length: 215 amino acids
Theoretical weight: 23.65 KDa
Source organism: Mus musculus
Expression system: Not provided
Structure domains: Immunoglobulins
Immunoglobulin heavy constant gamma 2A Chain: H
Molecule details ›
Chain: H
Length: 215 amino acids
Theoretical weight: 23.13 KDa
Source organism: Mus musculus
Expression system: Not provided
UniProt:
  • Canonical: P01865 (Residues: 1-99; Coverage: 25%)
Gene names: Igh-1a, Ighg2a
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P212121
Unit cell:
a: 83.7Å b: 110.7Å c: 56.3Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.19 0.19 not available
Expression system: Not provided

Quick links

Citations

26 review citations

Principles of protein-protein interactions.
Jones et al. (1996)
25 more

3 mentions without citation

FiberDock: Flexible induced-fit backbone refinement in molecular docking.
Mashiach et al. (2010)
2 more