PDBe 1g0o

X-ray diffraction
1.7Å resolution

STRUCTURE OF TRIHYDROXYNAPHTHALENE REDUCTASE IN COMPLEX WITH NADPH AND PYROQUILON

Released:

Function and Biology Details

Reaction catalysed:
Scytalone + NADP(+) = 1,3,6,8-tetrahydroxynaphthalene + NADPH
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tetrahydroxynaphthalene reductase Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 283 amino acids
Theoretical weight: 30.18 KDa
Source organism: Magnaporthe grisea
Expression system: Escherichia coli
UniProt:
  • Canonical: Q12634 (Residues: 1-283; Coverage: 100%)
Gene name: MGG_02252
Sequence domains:
Structure domains: NAD(P)-binding Rossmann-like Domain

Ligands and Environments


Cofactor: Ligand NDP 4 x NDP
1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: P212121
Unit cell:
a: 65Å b: 143.3Å c: 141.3Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.176 0.176 0.213
Expression system: Escherichia coli