› 7jmg

Electron Microscopy
4.5Å resolution

Functional Pathways of Biomolecules Retrieved from Single-particle Snapshots - Frame 22 - State 2 (S2)

Released:
DOI: 10.2210/pdb7jmg/pdb
PDB entry 7jmg coloured by chain, front view.
PDB entry 7jmg coloured by chain, side view.
PDB entry 7jmg coloured by chain, top view.
Source organisms:
Primary publication:
Retrieving functional pathways of biomolecules from single-particle snapshots.
Dashti A, Mashayekhi G, Shekhar M, Ben Hail D, Salah S, Schwander P, des Georges A, Singharoy A, Frank J, Ourmazd A
OpenAccess logo Nat Commun 11 4734 (2020)
PMID: 32948759
Related structures: EMD-22393

Function and Biology Details

Reaction catalysed: 
Peptidylproline (omega=180) = peptidylproline (omega=0)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero octamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-159293 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
ryanodine receptor type 1 Chains: B, E, G, I
Molecule details ›
Chains: B, E, G, I
Length: 4687 amino acids
Theoretical weight: 502.25 KDa
Source organism: Oryctolagus cuniculus
Peptidyl-prolyl cis-trans isomerase FKBP1B Chains: A, F, H, J
Molecule details ›
Chains: A, F, H, J
Length: 107 amino acids
Theoretical weight: 11.67 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P68106 (Residues: 2-108; Coverage: 99%)
Gene names: FKBP12.6, FKBP1B, FKBP1L, FKBP9, OTK4
Sequence domains: FKBP-type peptidyl-prolyl cis-trans isomerase

Ligands and Environments

2 bound ligands:
Ligand ZN 4 x ZN
Ligand CA 4 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 4.5Å
Relevant EMDB volumes: EMD-22393
Expression system: Escherichia coli

Quick links

Citations

11 review citations

Moving beyond static snapshots: Protein dynamics and the Protein Data Bank.
Miller et al. (2021)
10 more