› 3nq4

X-ray diffraction
3.5Å resolution

30mer structure of Lumazine synthase from Salmonella typhimurium LT2

Released:
DOI: 10.2210/pdb3nq4/pdb
PDB entry 3nq4 coloured by chain, front view.
PDB entry 3nq4 coloured by chain, side view.
PDB entry 3nq4 coloured by chain, top view.
Source organism: Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
Entry authors: Kumar P, Singh M, Karthikeyan S

Function and Biology Details

Reaction catalysed: 
1-deoxy-L-glycero-tetrulose 4-phosphate + 5-amino-6-(D-ribitylamino)uracil = 6,7-dimethyl-8-(D-ribityl)lumazine + 2 H(2)O + phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo 60-mer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-159188 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
6,7-dimethyl-8-ribityllumazine synthase Chains: 1, 2, 3, 4, A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X, Y, Z
Molecule details ›
Chains: 1, 2, 3, 4, A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X, Y, Z
Length: 156 amino acids
Theoretical weight: 16.02 KDa
Source organism: Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
Expression system: Escherichia coli
UniProt:
  • Canonical: P66038 (Residues: 1-156; Coverage: 100%)
Gene names: STM0417, ribH
Sequence domains: 6,7-dimethyl-8-ribityllumazine synthase
Structure domains: Lumazine/riboflavin synthase

Ligands and Environments

1 bound ligand:
Ligand SO4 40 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Unit cell:
a: 174.43Å b: 157.49Å c: 202.788Å
α: 90° β: 91.58° γ: 90°
R-values:
R R work R free
0.256 0.255 0.299
Expression system: Escherichia coli

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