› 2f6h

X-ray diffraction
2.25Å resolution

Myosin V cargo binding domain

Released:
DOI: 10.2210/pdb2f6h/pdb
PDB entry 2f6h coloured by chain, front view.
PDB entry 2f6h coloured by chain, side view.
PDB entry 2f6h coloured by chain, top view.
Source organism: Saccharomyces cerevisiae
Primary publication:
Structural basis for myosin V discrimination between distinct cargoes.
Pashkova N, Jin Y, Ramaswamy S, Weisman LS
EMBO J 25 693-700 (2006)
PMID: 16437158

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-148623 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Myosin-2 Chain: X
Molecule details ›
Chain: X
Length: 419 amino acids
Theoretical weight: 47.99 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli
UniProt:
  • Canonical: P19524 (Residues: 1152-1570; Coverage: 27%)
Gene names: CDC66, MYO2, O6167, YOR326W
Sequence domains: DIL domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 17-ID
Spacegroup: P212121
Unit cell:
a: 50.78Å b: 72.673Å c: 167.982Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.219 0.217 0.25
Expression system: Escherichia coli

Quick links

Citations

26 review citations

Tethering factors as organizers of intracellular vesicular traffic.
Yu et al. (2010)
25 more

16 mentions without citation

Myosin V from head to tail.
Trybus KM. (2008)
15 more