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"accession": "MGYS00002077",
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"last-update": "2019-11-07T16:56:42",
"secondary-accession": "SRP074222",
"centre-name": "College of Veterinary Medicine, Illinois university",
"public-release-date": null,
"study-abstract": "Bovine respiratory disease (BRD) is a major cause of morbidity, mortality and economic loss in the US cattle industry. In view of the importance of this disease complex, and the need to reduce antimicrobial use in food producing animals, there is growing interest in developing novel strategies to enhance host immune defenses against respiratory pathogens. The cooperative interactions between microbes and their hosts have been recognized for years, and there is increasing evidence that mucosal bacterial populations act, not only as a reservoir of potential pathogens, but also in regulating local and systemic immune homeostasis through a complex cross talk with the epithelium, local immune system and mucosal neuronal pathways. In this study we used culture-independent techniques to characterize the nasopharyngeal microbiome of cattle during the initial processing phase in the commercial feedlot. In addition, we compared the dynamics of change in these microbial communities, between clinically healthy calves and those that develop BRD within the first month of entry in to the feedlot.",
"study-name": "Characterization of the nasopharyngeal microbiota in naturally occurring respiratory disease in feedlot cattle",
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