GET /metagenomics/api/v1/samples/SRS1223314/studies?format=api
HTTP 200 OK
Allow: GET, HEAD, OPTIONS
Content-Type: application/json
Vary: Accept
{
"links": {
"first": "https://www.ebi.ac.uk/metagenomics/api/v1/samples/SRS1223314/studies?format=api&page=1",
"last": "https://www.ebi.ac.uk/metagenomics/api/v1/samples/SRS1223314/studies?format=api&page=1",
"next": null,
"prev": null
},
"data": [
{
"type": "studies",
"id": "MGYS00001252",
"attributes": {
"accession": "MGYS00001252",
"bioproject": "PRJNA306884",
"samples-count": 157,
"is-private": false,
"last-update": "2016-10-04T16:29:21",
"secondary-accession": "SRP067761",
"centre-name": "University of Michigan",
"public-release-date": null,
"study-abstract": "Colonic bacteria produce the health-promoting metabolite butyrate. We sought to influence butyrate production in 20 healthy adults by supplementing their diet with resistant starch (RS). While average fecal butyrate increased from 8 to 12 mmol/kg wet feces, responses varied widely between individuals. Three types of responses were categorized: enhanced, high, and low (n = 11, 3, and 6 respectively). Fecal butyrate increased by 87% in the enhanced group, while it remained =12 mmol/kg in the high group and =8 mmol/kg in the low group. Microbiome analyses revealed that RS-degrading organisms increased from ~ 2 to 10% in the enhanced and high groups, but remained at ~ 2% in the low group. This lack of increase in RS-degrading microbes is likely why individuals in the low group do not benefit in butyrate with RS. This study underscores the importance of understanding inter-individual variability in managing ecosystem services from microbiomes.",
"study-name": "Managing human microbiomes: Explaining heterogeneous responses in butyrate to dietary supplementation with resistant starch",
"data-origination": "HARVESTED"
},
"relationships": {
"downloads": {
"links": {
"related": "https://www.ebi.ac.uk/metagenomics/api/v1/studies/MGYS00001252/downloads?format=api"
}
},
"geocoordinates": {
"links": {
"related": "https://www.ebi.ac.uk/metagenomics/api/v1/studies/MGYS00001252/geocoordinates?format=api"
}
},
"analyses": {
"links": {
"related": "https://www.ebi.ac.uk/metagenomics/api/v1/studies/MGYS00001252/analyses?format=api"
}
},
"biomes": {
"links": {
"related": "https://www.ebi.ac.uk/metagenomics/api/v1/studies/MGYS00001252/biomes?format=api"
},
"data": [
{
"type": "biomes",
"id": "root:Host-associated:Human:Digestive system:Large intestine:Fecal",
"links": {
"self": "https://www.ebi.ac.uk/metagenomics/api/v1/biomes/root:Host-associated:Human:Digestive%20system:Large%20intestine:Fecal?format=api"
}
}
]
},
"publications": {
"links": {
"related": "https://www.ebi.ac.uk/metagenomics/api/v1/studies/MGYS00001252/publications?format=api"
}
},
"samples": {
"links": {
"related": "https://www.ebi.ac.uk/metagenomics/api/v1/studies/MGYS00001252/samples?format=api"
}
}
},
"links": {
"self": "https://www.ebi.ac.uk/metagenomics/api/v1/studies/MGYS00001252?format=api"
}
}
],
"meta": {
"pagination": {
"page": 1,
"pages": 1,
"count": 1
}
}
}