Sample Studies Relationship List

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        {
            "type": "studies",
            "id": "MGYS00000569",
            "attributes": {
                "accession": "MGYS00000569",
                "bioproject": "PRJEB11804",
                "samples-count": 24,
                "is-private": false,
                "last-update": "2016-02-03T10:02:09",
                "secondary-accession": "ERP013213",
                "centre-name": "IBERS",
                "public-release-date": null,
                "study-abstract": "There is an increasing need to identify alternative feeds for livestock that do not compete with feeds for human consumption. Seaweed might provide such a resource, but there is limited information available on its value as an animal feed. Here we use a multi-omics approach to investigate the value of two brown seaweeds, Ascophyllum nodosum (ASC) and Laminaria digitata (LAM), as alternative feeds for ruminants. These seaweeds were supplemented at 5% inclusion rate into a control diet (CON) in a rumen simulation fermenter. Seaweeds had no substantial effect on rumen fermentation pattern, feed digestibility or methane emissions in vitro. Concentrations of total bacteria and anaerobic fungi, as well as biodiversity indices, and abundance of the main bacterial and methanogens genera were also unaffected by brown seaweed supplementation. However, specie-specific effects of brown seaweed on the rumen function were noted: ASC promoted a substantial decrease in the N digestibility (-24%) as a result of its high phlorotannins content. Canonical correspondence analysis of the bacterial community revealed that the low N availability led to a change in the structure of the bacterial community. ASC also decreased the concentration of Escherichia coli O157:H7 post-inoculation. On the contrary, LAM which has a much lower phlorotannins content did not cause detrimental effects on N digestibility nor modified the structure of the bacterial community in comparison to CON diets. This adaptation of the microbial community to LAM diets led to a greater microbial ability to digest xylan (+70%) and carboxy-methyl-cellulose (+41%). These differences among brown seaweeds resulted in greater microbial protein synthesis (+15%) and non-ammonia N flow (+11%) in LAM than in ASC diets and thus should led to a greater amino acid supply to the intestine of the animal. In conclusion, it was demonstrated that incorporation of 5% brown seaweed into the diet can be considered as a suitable nutritional strategy for ruminants; however special care must be taken with those seaweeds with high phlorotannins content to prevent detrimental effects on N metabolism. This study demonstrates the value of combining fermentation data with molecular characterisation of the rumen microbiome in evaluating novel feeds for ruminants.",
                "study-name": "A metagenomics approach to evaluate the impact of Ascophyllum nodosum and Laminaria digitata on the rumen function",
                "data-origination": "SUBMITTED"
            },
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                    "data": [
                        {
                            "type": "biomes",
                            "id": "root:Host-associated:Mammals:Digestive system:Stomach:Rumen",
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