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"id": "MGYS00006091",
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"accession": "MGYS00006091",
"bioproject": "PRJEB31015",
"samples-count": 40,
"is-private": false,
"last-update": "2022-12-13T15:18:47",
"secondary-accession": "ERP113521",
"centre-name": "UNIVERSITY COLLEGE DUBLIN",
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"study-abstract": "Alterations between microbial profiles are potentially a key factor influencing feed efficiency in pigs. The objective of this study was to identify if differences in microbial diversity, relative abundance of taxa exist within the intestinal microbiota of pigs divergent in feed efficiency selected from two different farms of origin. Two populations of pigs were used in this study with piglets selected from two different farms of origin (Group A and B). In Group A, the 8 most efficient (LRFI) and 8 least efficient (HRFI) animals were selected for further analysis, while in Group B the 12 most efficient and 12 least efficient were utilised. Colonic digesta was collected from these pigs to analyse the intestinal microbiota using 16S rRNA gene sequencing. 106 of 126 identified taxa in this study differed between groups while a small number of taxa differed based on feed efficiency. Alpha diversity differed between the two groups in this study with pigs from Group A having increased alpha diversity based on Shannon and InvSimpson measures compared to pigs from Group B (P<0.05). Between HRFI and LRFI pigs across the two groups, no differences in any measures of Alpha diversity were identified (P>0.10). In agreement with these findings, beta diversity analysis established that pigs grouped based on farm of origin rather than RFI group. Within the Bacteroidetes phylum the LRFI pigs had increased BS11 (P<0.05) and tended to have increased Bacteroidaceae (P<0.10) at family level while at genus level the LRFI pigs tended to have increased Bacteroides and CF231 (P<0.10). The increased abundance of these taxa suggest an increased capacity of the more efficient pigs to breakdown feed potentially impacting nutrient digestibility. The changes identified in this study suggest an influence of the microbiome in influencing feed efficiency. However, the differences between groups suggest that these results need to be corroborated in larger studies across multiple environments.",
"study-name": "An examination of the intestinal microbiome of pigs divergent in feed efficiency",
"data-origination": "SUBMITTED"
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