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"last-update": "2024-06-28T21:01:05",
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"study-abstract": "The Gut microbial dysbiosis in young adults with obesity Third Party Annotation (TPA) assembly was derived from the primary whole genome shotgun (WGS) data set: PRJEB12123. This project includes samples from the following biomes: Host-associated, Human, Digestive system, Large intestine, Fecal.",
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"last-update": "2020-05-17T09:56:00",
"secondary-accession": "ERP013562",
"centre-name": "BGI",
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"study-abstract": "Obesity has become a global epidemic as a high risk factor for type 2 diabetes, cardiovascular diseases and cancer. Besides human genetics, our gut microbiome is another contributor to human obesity. Here we perform metagenome-wide association studies (MGWAS) on fecal samples from a case-control cohort including 95 Chinese young adults with obesity and 105 normal-weight controls, and 23 obese patients after weight-loss treatment. We discover and validate microbial species deregulated in obesity, and show the changes of gut microbial composition after weight-loss treatment.",
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