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{
"metadata": {
"accession": "Q9SJI9",
"id": "PCO4_ARATH",
"source_organism": {
"taxId": "3702",
"scientificName": "Arabidopsis thaliana",
"fullName": "Arabidopsis thaliana (Mouse-ear cress)"
},
"name": "Plant cysteine oxidase 4",
"description": [
"Catalyzes the oxidation of N-terminal cysteine residues (N-Cys), thus preparing the protein for N-end rule pathway-mediated proteasomal degradation, upstream of the N-end rule enzymes ATE1, ATE2 and PRT6 (Probable) (PubMed:28332493, PubMed:29848548, PubMed:32868422, PubMed:33207269). Controls the preparation of the group VII ethylene response factor (ERF-VII) proteins for degradation via the 26S proteasome N-end rule pathway (Probable) (PubMed:28332493, PubMed:29848548, PubMed:32868422, PubMed:33207269). Acts as an oxygen sensor that controls the stability of ERF-VII proteins, which are stabilized in flooding-induced hypoxia, and regulate transcriptional adaptation to these adverse conditions (PubMed:28332493, PubMed:29848548)"
],
"length": 241,
"sequence": "MPYFAQRLYNTCKASFSSDGPITEDALEKVRNVLEKIKPSDVGIEQDAQLARSRSGPLNERNGSNQSPPAIKYLHLHECDSFSIGIFCMPPSSMIPLHNHPGMTVLSKLVYGSMHVKSYDWLEPQLTEPEDPSQARPAKLVKDTEMTAQSPVTTLYPKSGGNIHCFKAITHCAILDILAPPYSSEHDRHCTYFRKSRREDLPGELEVDGEVVTDVTWLEEFQPPDDFVIRRIPYRGPVIRT",
"proteome": "UP000006548",
"gene": "PCO4",
"go_terms": [
{
"identifier": "GO:0016702",
"name": "oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen",
"category": {
"code": "F",
"name": "molecular_function"
}
}
],
"protein_evidence": 1,
"source_database": "reviewed",
"is_fragment": false,
"in_alphafold": true,
"in_bfvd": false,
"ida_accession": "d4b7758babc4823e93df4117bf6fd436c4ddfa66",
"counters": {
"domain_architectures": 5758,
"entries": 8,
"isoforms": 2,
"proteomes": 1,
"sets": 2,
"structures": 3,
"taxa": 1,
"dbEntries": {
"ssf": 1,
"cathgene3d": 1,
"cdd": 1,
"panther": 1,
"pfam": 1,
"interpro": 3
},
"proteome": 1,
"taxonomy": 1,
"similar_proteins": 5758
}
}
}