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{
    "metadata": {
        "accession": "Q9JJL3",
        "id": "SO1B2_MOUSE",
        "source_organism": {
            "taxId": "10090",
            "scientificName": "Mus musculus",
            "fullName": "Mus musculus (Mouse)"
        },
        "name": "Solute carrier organic anion transporter family member 1B2",
        "description": [
            "Mediates the Na(+)-independent uptake of organic anions such as taurochlate, bromosulfophthalein and steroid conjugates (estrone 3-sulfate, 17-beta-glucuronosyl estradiol, dehydroepiandrosterone sulfate). Also transports prostaglandin E2 and L-thyroxine (T4). Shows a pH-sensitive substrate specificity which may be ascribed to the protonation state of the binding site and leads to a stimulation of substrate transport in an acidic microenvironment. Hydrogencarbonate/HCO3(-) acts as the probable counteranion that exchanges for organic anions"
        ],
        "length": 689,
        "sequence": "MDQTQHPSKAAQPLRSEKTRHCDGFRIFLAALSFSYICKALGGVIMKSSITQIERRFDIPSSISGLIDGGFEIGNLLVIVFVSYFGSKLHRPKLIGTGCFIMGIGSILTALPHFFMGYYRYATENDISSLHNSTLTCLVNQTTSLTGTSPEIMEKGCEKGSNSYTWIYVLMGNMLRGIGETPIVPLGVSYIDDFAKEGNSSMYLGTLHTIAMIGPILGFIMSSVFAKLYVDVGYVDLRSVRITPQDARWVGAWWLGFIVNGLLCIICSIPFFFLPKIPKRSQKERKNSASLHVLKTDEDKNPVTNPTTQEKQAPANLTGFLWSLRSILTNEQYVIFLILTLLQISSFIGSFTYLFKFIEQQFGQTASQANFLLGVITIPTMASGMFLGGYLIKRLKLTLLGITKFVFFTTTMAYVFYLSYFLLICENKAFAGLTLTYDGMNPVDSHIDVPLSYCNSDCICDKNQWEPVCGENGVTYISPCLAGCKSFRGDKKLMNIEFYDCSCVSGSGFQKGNHSARLGECPRDKCKTKYYFYITFQVIISFFTALGSTSLMLILIRSVQPELKSLGMGFHSLVVRTLGGILAPVYYGALIDRTCMKWSVTSCGARGACRLYNSRLFGMIYVGLSIALKTPILLLYVALIYVMKRKMKRNDNKILENGRKFTDEGNPEPVNNNGYSCVPSDEKNSETPL",
        "proteome": "UP000000589",
        "gene": "Slco1b2",
        "go_terms": [
            {
                "identifier": "GO:0022857",
                "name": "transmembrane transporter activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0005515",
                "name": "protein binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0055085",
                "name": "transmembrane transport",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            },
            {
                "identifier": "GO:0016020",
                "name": "membrane",
                "category": {
                    "code": "C",
                    "name": "cellular_component"
                }
            }
        ],
        "protein_evidence": 1,
        "source_database": "reviewed",
        "is_fragment": false,
        "in_alphafold": true,
        "in_bfvd": false,
        "ida_accession": "9921360838b092afbbe83d58c42b78e1a41b29a1",
        "counters": {
            "domain_architectures": 11062,
            "entries": 16,
            "isoforms": 2,
            "proteomes": 1,
            "sets": 2,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "ssf": 2,
                "cathgene3d": 2,
                "profile": 2,
                "pfam": 2,
                "smart": 1,
                "panther": 1,
                "ncbifam": 1,
                "interpro": 5
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 11062
        }
    }
}