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{
    "metadata": {
        "accession": "Q3MHI4",
        "id": "PHAX_BOVIN",
        "source_organism": {
            "taxId": "9913",
            "scientificName": "Bos taurus",
            "fullName": "Bos taurus (Bovine)"
        },
        "name": "Phosphorylated adapter RNA export protein",
        "description": [
            "A phosphoprotein adapter involved in the XPO1-mediated U snRNA export from the nucleus. Bridge components required for U snRNA export, the cap binding complex (CBC)-bound snRNA on the one hand and the GTPase Ran in its active GTP-bound form together with the export receptor XPO1 on the other. Its phosphorylation in the nucleus is required for U snRNA export complex assembly and export, while its dephosphorylation in the cytoplasm causes export complex disassembly. It is recycled back to the nucleus via the importin alpha/beta heterodimeric import receptor. The directionality of nuclear export is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. Its compartmentalized phosphorylation cycle may also contribute to the directionality of export. Binds strongly to m7G-capped U1 and U5 small nuclear RNAs (snRNAs) in a sequence-unspecific manner and phosphorylation-independent manner. Also plays a role in the biogenesis of U3 small nucleolar RNA (snoRNA). Involved in the U3 snoRNA transport from nucleoplasm to Cajal bodies. Binds strongly to m7G-capped U3, U8 and U13 precursor snoRNAs and weakly to trimethylated (TMG)-capped U3, U8 and U13 snoRNAs. Also binds to telomerase RNA (By similarity)"
        ],
        "length": 394,
        "sequence": "MAQEAGDMDDGQVSDSDSDMTVAPSDRPLPVPKALGGDCGLRPFQSTATACAPASHYRTVKSVDSSEESFSDSDDDSSVWKRKRQKCFNTPPKPEPFQFDQSSQKPPIAGRKKVNNIWSAVLQEQNQDAVATELGILGMEGTIDRSRQSETYNYLLAKKLKRESQEHTKELDKELEEYMHGGKKTGPKEEENGQGHPKRKRPVKDRVGDRLEMNYKGRYEITEDDSQERVADEISFRLQEPKKDLIARVVRIIGNKKAIELLMETAEVEQNGGLFIMNGSRRRTPGGVFLNLLKNTPSISEEQIKDIFYLENQKEYENKKAARKRRIQVMGKKMKQAIKNLNFQEDDDTSRETFASDTNEALASLDESQEGHGETKLDAEEAIEVDHSHDLDMF",
        "proteome": "UP000009136",
        "gene": "PHAX",
        "go_terms": [
            {
                "identifier": "GO:0006408",
                "name": "snRNA export from nucleus",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            }
        ],
        "protein_evidence": 2,
        "source_database": "reviewed",
        "is_fragment": false,
        "in_alphafold": true,
        "in_bfvd": false,
        "ida_accession": "c62a24f2a5048b3359bfb99cebb1bc2f65a149b4",
        "counters": {
            "domain_architectures": 2286,
            "entries": 6,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 0,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "cathgene3d": 1,
                "pfam": 1,
                "panther": 1,
                "interpro": 3
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 2286
        }
    }
}