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Content-Type: application/json
InterPro-Version: 108.0
InterPro-Version-Minor: 0
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{
    "metadata": {
        "accession": "Q2ET08",
        "id": "OSPF_SHIDY",
        "source_organism": {
            "taxId": "622",
            "scientificName": "Shigella dysenteriae",
            "fullName": "Shigella dysenteriae"
        },
        "name": "Phosphothreonine lyase OspF",
        "description": [
            "Catalyzes the removal of the phosphate group from the phosphothreonine in the mitogen-activated protein kinases such as MAPK2/ERK2, MAPK3/ERK1, MAPK8 and MAPK14 in an irreversible reaction, thus preventing the downstream phosphorylation of histone H3. This epigenetic modification results in inhibition of the transcription of a specific subset of pro-inflammatory genes, and ultimately to a reduced immune response against the invading pathogen. The diminished immune response enhances the bacterium's ability to disseminate and multiply within the host (By similarity)"
        ],
        "length": 170,
        "sequence": "PQMLSANERLKNNFNILYNQIRQYPAYYFKVASNVPTYSDICQFFSVMYQGFQIVNHSGDVFIHACRENPQSKGDFVGDKFHISIAREQVPLAFQILSGLLFSEDSPIDKWKITDMNRVSQQSRVGIGAQFTLYVKSDQECSQYSALLLHKIRQFIMCLESNLLRSKIAP",
        "proteome": null,
        "gene": "ospF",
        "go_terms": null,
        "protein_evidence": 3,
        "source_database": "reviewed",
        "is_fragment": true,
        "in_alphafold": true,
        "in_bfvd": false,
        "ida_accession": "8235289369967b6b8159705328d07e9d345661c7",
        "counters": {
            "domain_architectures": 330,
            "entries": 6,
            "isoforms": 0,
            "proteomes": 0,
            "sets": 1,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "cathgene3d": 1,
                "ncbifam": 1,
                "pfam": 1,
                "prints": 1,
                "interpro": 2
            },
            "proteome": 0,
            "taxonomy": 1,
            "similar_proteins": 330
        }
    }
}