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InterPro-Version: 108.0
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{
"metadata": {
"accession": "Q0IHT3",
"id": "CRTC3_XENTR",
"source_organism": {
"taxId": "8364",
"scientificName": "Xenopus tropicalis",
"fullName": "Xenopus tropicalis (Western clawed frog)"
},
"name": "CREB-regulated transcription coactivator 3",
"description": [
"Transcriptional coactivator for creb1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of creb1 'Ser-119' phosphorylation. Enhances the interaction of creb1 with taf4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of ppargc1a and inducer of mitochondrial biogenesis in muscle cells (By similarity)"
],
"length": 637,
"sequence": "MAATPAASGSNPRKFSEKIALHNQKQAEETRAFDELMSDLTVSRVQFQKLQQLRLAQSRAQYYGGSLPNVNQISSSPTDFQPSFHPTDNIRGMRHHGLVERVSRNRLHSSHHRPIEKHGRQCDSSPYGSVYLSPPPDNNWRRTNSDSALHTSASSTKSQDPFMGGAQAMLRAPKPPQRNTSLQDGEIDNFGEVFSFPNAMTEENMLNVTKPLPKQIWEAQKVQCITSRPRSCEVPNIKVFPSSDSNASLSHFQGSLNTGGSLPDLTNLHFPSPLPTPLDPDDTAYANISAENSSGLPAAMTHLGISGSPGMQNTRSNPSIQATMNNNSLASNVNSHTPPGRNNPALHPSLRLSSLSNPSLPTSALGTSPRRRHTPVSPLTLTPGSESNRSISNQFSPTSPMNMPPNSQGVSMDRSPLSLPPLEPPPPYPLYSDQPQPHLHHTQQQMHESLDSQNYQPPSPVPCPPLDLNLANSSLSGFFGDSFFDQQQPTKQGKYLWQQQEQYDMFGSPSSSLPNTNAFFDPNMNLQYSQASLMGLGGSHGSLQDSFHLRPNYLYSNCGGSVPNIILTDDSSNSLSKDISNAVAGVSELGFDADNTFQLDDELKLGPLSLDGLSMLSDPDMVLPDPSIEDSFRSDKL",
"proteome": "UP000008143",
"gene": "crtc3",
"go_terms": [
{
"identifier": "GO:0005634",
"name": "nucleus",
"category": {
"code": "C",
"name": "cellular_component"
}
},
{
"identifier": "GO:0005737",
"name": "cytoplasm",
"category": {
"code": "C",
"name": "cellular_component"
}
},
{
"identifier": "GO:0008140",
"name": "cAMP response element binding protein binding",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0051289",
"name": "protein homotetramerization",
"category": {
"code": "P",
"name": "biological_process"
}
}
],
"protein_evidence": 2,
"source_database": "reviewed",
"is_fragment": false,
"in_alphafold": true,
"in_bfvd": false,
"ida_accession": "3148b27c77231e098c12fc5f0c5af7f632beff08",
"counters": {
"domain_architectures": 2107,
"entries": 8,
"isoforms": 0,
"proteomes": 1,
"sets": 0,
"structures": 0,
"taxa": 1,
"dbEntries": {
"panther": 1,
"pfam": 3,
"interpro": 4
},
"proteome": 1,
"taxonomy": 1,
"similar_proteins": 2107
}
}
}