General Handler

HTTP 200 OK
Allow: GET, HEAD
Content-Type: application/json
InterPro-Version: 108.0
InterPro-Version-Minor: 0
Vary: Accept

{
    "metadata": {
        "accession": "P56273",
        "id": "MDM2_XENLA",
        "source_organism": {
            "taxId": "8355",
            "scientificName": "Xenopus laevis",
            "fullName": "Xenopus laevis (African clawed frog)"
        },
        "name": "E3 ubiquitin-protein ligase Mdm2",
        "description": [
            "E3 ubiquitin-protein ligase that mediates ubiquitination of p53/TP53, leading to its degradation by the proteasome"
        ],
        "length": 473,
        "sequence": "MNLTSTTNCLENNHISTSDQEKLVQPTPLLLSLLKSAGAQKETFTMKEVIYHLGQYIMAKQLYDEKQQHIVHCSNDPLGELFGVQEFSVKEPRRLYAMISRNLVSANVKESSEDIFGNVCCFPDKQSSQKEKLQELPDKLIAPASDSKPCNLSQRKSSNETEEISSVDHPAEQQRKRHKSDSFSLTFDESLSWWVISGLRCDRNSSESTDSSSNSDPERHSTNDNSEHDSDQFSVEFEVESVCSDDYSPSGDEHGVSEEEEINDEVYQVTIYETEESETDSFDVDTEISEADYWKCPECGEVNPPLPSYCPRCWTVRKDWLPEQRRKEPPPSKRKLLEIEEDEGFDVPDCKKSKLTSSQDTNVDKKEAENIQNSESQETEDCSQPSTSGSIASCSQEVTKEDSSKESMESSLPLTSIDPCVICQTRPKNGCIVHGRTGHLMACYTCAKKLKKRNKPCPVCREPIQMIVLTYFS",
        "proteome": "UP000186698",
        "gene": "mdm2",
        "go_terms": [
            {
                "identifier": "GO:0042802",
                "name": "identical protein binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0061630",
                "name": "ubiquitin protein ligase activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0043066",
                "name": "negative regulation of apoptotic process",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            },
            {
                "identifier": "GO:0051726",
                "name": "regulation of cell cycle",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            },
            {
                "identifier": "GO:0005634",
                "name": "nucleus",
                "category": {
                    "code": "C",
                    "name": "cellular_component"
                }
            }
        ],
        "protein_evidence": 1,
        "source_database": "reviewed",
        "is_fragment": false,
        "in_alphafold": true,
        "in_bfvd": false,
        "ida_accession": "37973506204de2200c471ef6d28d09548fc718e5",
        "counters": {
            "domain_architectures": 854,
            "entries": 27,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 6,
            "structures": 12,
            "taxa": 1,
            "dbEntries": {
                "cathgene3d": 3,
                "ssf": 3,
                "cdd": 2,
                "profile": 3,
                "pfam": 3,
                "pirsf": 2,
                "panther": 1,
                "prosite": 1,
                "interpro": 9
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 854
        }
    }
}