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InterPro-Version: 108.0
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{
"metadata": {
"accession": "M3ZAF7",
"id": "M3ZAF7_NOMLE",
"source_organism": {
"taxId": "61853",
"scientificName": "Nomascus leucogenys",
"fullName": "Nomascus leucogenys (Northern white-cheeked gibbon)"
},
"name": "AP complex subunit beta",
"description": [
"Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asymmetric localization of somatodendritic proteins in neurons. AP-4 is involved in the recognition and binding of tyrosine-based sorting signals found in the cytoplasmic part of cargos, but may also recognize other types of sorting signal"
],
"length": 571,
"sequence": "MPYLGSEDVVKELKKALCNPHIQSDRLRYRNVIQRVIRMSKLDQWGQAEVLNFLLRYQPRSEEELFDILNLLDSFLKSSSPGVVMGATKLFLILAKKFPHVQTDVLVRVKGPLLAACSSESRELCFVALCHVRQILHSLPGHFSSHYKKFFCSYSEPHYIKLQKVEVLCELVNDENVQQVLEELRGYCTDVSADFAQAAIFAIGGIARTYTDQCVQILTELLGLRQEHITTVVVQTFRDLVWLCPQCTEAVCQALPGCEENIQDSEGKQALIWLLGVHGERIPNAPYVLEDFVENVKSETFPAVKMELLTALLRLFLSRPAECQDVLGRLLYYCIEEEKDMAVRDRGLFYYRLLLVGIDEVKRILCSPKSDPTLGLLEDPAERPVNSWASDFNTLVPVYGKAHWATISKCQGAECCGPELPKTSSFAASGPLIPEENKERVQELPDSGALMLVPNHQLTADYFEKTWLSLKVAHQQVLPWRGEFHPDTLQMALQVVNIQTIAMSRAGSRPWKAYLSAQDDTGCLFLTELLLEPENSEMQISVKQSEARTETLNSFISVLETVIGTIEEIKS",
"proteome": "UP000001073",
"gene": "AP4B1",
"go_terms": [
{
"identifier": "GO:0006886",
"name": "intracellular protein transport",
"category": {
"code": "P",
"name": "biological_process"
}
},
{
"identifier": "GO:0016192",
"name": "vesicle-mediated transport",
"category": {
"code": "P",
"name": "biological_process"
}
},
{
"identifier": "GO:0030117",
"name": "membrane coat",
"category": {
"code": "C",
"name": "cellular_component"
}
},
{
"identifier": "GO:0030131",
"name": "clathrin adaptor complex",
"category": {
"code": "C",
"name": "cellular_component"
}
},
{
"identifier": "GO:0030276",
"name": "clathrin binding",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0015031",
"name": "protein transport",
"category": {
"code": "P",
"name": "biological_process"
}
}
],
"protein_evidence": 3,
"source_database": "unreviewed",
"is_fragment": false,
"in_alphafold": true,
"in_bfvd": false,
"ida_accession": "343081db5317ff361a69a3ea55b33f3c1c1c9551",
"counters": {
"domain_architectures": 2021,
"entries": 15,
"isoforms": 0,
"proteomes": 1,
"sets": 2,
"structures": 0,
"taxa": 1,
"dbEntries": {
"cathgene3d": 2,
"pfam": 2,
"ssf": 1,
"smart": 1,
"pirsf": 1,
"panther": 1,
"interpro": 7
},
"proteome": 1,
"taxonomy": 1,
"similar_proteins": 2021
}
}
}