{"metadata":{"accession":"M3ZAF7","id":"M3ZAF7_NOMLE","source_organism":{"taxId":"61853","scientificName":"Nomascus leucogenys","fullName":"Nomascus leucogenys (Northern white-cheeked gibbon)"},"name":"AP complex subunit beta","description":["Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asymmetric localization of somatodendritic proteins in neurons. AP-4 is involved in the recognition and binding of tyrosine-based sorting signals found in the cytoplasmic part of cargos, but may also recognize other types of sorting signal"],"length":571,"sequence":"MPYLGSEDVVKELKKALCNPHIQSDRLRYRNVIQRVIRMSKLDQWGQAEVLNFLLRYQPRSEEELFDILNLLDSFLKSSSPGVVMGATKLFLILAKKFPHVQTDVLVRVKGPLLAACSSESRELCFVALCHVRQILHSLPGHFSSHYKKFFCSYSEPHYIKLQKVEVLCELVNDENVQQVLEELRGYCTDVSADFAQAAIFAIGGIARTYTDQCVQILTELLGLRQEHITTVVVQTFRDLVWLCPQCTEAVCQALPGCEENIQDSEGKQALIWLLGVHGERIPNAPYVLEDFVENVKSETFPAVKMELLTALLRLFLSRPAECQDVLGRLLYYCIEEEKDMAVRDRGLFYYRLLLVGIDEVKRILCSPKSDPTLGLLEDPAERPVNSWASDFNTLVPVYGKAHWATISKCQGAECCGPELPKTSSFAASGPLIPEENKERVQELPDSGALMLVPNHQLTADYFEKTWLSLKVAHQQVLPWRGEFHPDTLQMALQVVNIQTIAMSRAGSRPWKAYLSAQDDTGCLFLTELLLEPENSEMQISVKQSEARTETLNSFISVLETVIGTIEEIKS","proteome":"UP000001073","gene":"AP4B1","go_terms":[{"identifier":"GO:0006886","name":"intracellular protein transport","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0016192","name":"vesicle-mediated transport","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0030117","name":"membrane coat","category":{"code":"C","name":"cellular_component"}},{"identifier":"GO:0030131","name":"clathrin adaptor complex","category":{"code":"C","name":"cellular_component"}},{"identifier":"GO:0030276","name":"clathrin binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0015031","name":"protein transport","category":{"code":"P","name":"biological_process"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"343081db5317ff361a69a3ea55b33f3c1c1c9551","counters":{"domain_architectures":2021,"entries":15,"isoforms":0,"proteomes":1,"sets":2,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":2,"pfam":2,"ssf":1,"smart":1,"pirsf":1,"panther":1,"interpro":7},"proteome":1,"taxonomy":1,"similar_proteins":2021}}}