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{
"metadata": {
"accession": "K4G0J8",
"id": "K4G0J8_CALMI",
"source_organism": {
"taxId": "7868",
"scientificName": "Callorhinchus milii",
"fullName": "Callorhinchus milii (Ghost shark)"
},
"name": "Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial",
"description": [
"Dihydrolipoamide succinyltransferase (E2) component of the 2-oxoglutarate dehydrogenase complex. The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). The 2-oxoglutarate dehydrogenase complex is mainly active in the mitochondrion. A fraction of the 2-oxoglutarate dehydrogenase complex also localizes in the nucleus and is required for lysine succinylation of histones: associates with KAT2A on chromatin and provides succinyl-CoA to histone succinyltransferase KAT2A"
],
"length": 463,
"sequence": "MFARCRSVSRSLSRWAVTRRPGALQASGSLGRRALSGLSVGHRVVNNNRQFQENVSKFRIFHIRHFKTSAVFNDEVMTVNTPAFAESVTEGDVRWEKAVGDTVAEDEVVCEIETDKTAVQVPAPHAGVIEELLVPDGGKVEGGTPLFKLRKTQAGAAKPKAAEAPTAPQPAVTPPSAPAHSTGPIPTTMPPVPQVSTQPMDSKPVSAVKASAVPAGFSVEAPDAGLKGGRSEHKVKMNRMRLRIAQRLKESQNTCAMLTTFNEIDMSNIQEMRALHKETFLKKHNMKLGFMSAFVKAASFALQNQPVVNAVIDDSTKEIIYREYIDISVAVATPKGLVVPVIRNVEMMNFADIEKAINELGEKARKNELAVEDMDGGTFTISNGGVFGSLFGTPIINPPQSAILGMHGIFQRPVAIQGKVEIRPMMYVALTYDHRLIDGREAVMFLRKVKAVVEDPRVLLLDI",
"proteome": "UP000314986",
"gene": "dlst",
"go_terms": [
{
"identifier": "GO:0016746",
"name": "acyltransferase activity",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0004149",
"name": "dihydrolipoyllysine-residue succinyltransferase activity",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0006099",
"name": "tricarboxylic acid cycle",
"category": {
"code": "P",
"name": "biological_process"
}
},
{
"identifier": "GO:0045252",
"name": "oxoglutarate dehydrogenase complex",
"category": {
"code": "C",
"name": "cellular_component"
}
}
],
"protein_evidence": 2,
"source_database": "unreviewed",
"is_fragment": false,
"in_alphafold": true,
"in_bfvd": false,
"ida_accession": "696e27af6f82e2120b0f8a44f2233f48ae538bfa",
"counters": {
"domain_architectures": 7190,
"entries": 19,
"isoforms": 0,
"proteomes": 1,
"sets": 3,
"structures": 0,
"taxa": 1,
"dbEntries": {
"cathgene3d": 2,
"profile": 1,
"ssf": 2,
"cdd": 1,
"pfam": 2,
"panther": 1,
"ncbifam": 2,
"prosite": 1,
"interpro": 7
},
"proteome": 1,
"taxonomy": 1,
"similar_proteins": 7190
}
}
}