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{
    "metadata": {
        "accession": "H9ZEM3",
        "id": "H9ZEM3_MACMU",
        "source_organism": {
            "taxId": "9544",
            "scientificName": "Macaca mulatta",
            "fullName": "Macaca mulatta (Rhesus macaque)"
        },
        "name": "3'-5' exoribonuclease HELZ2",
        "description": [
            "Can degrade highly structured RNAs through its concerted ATP-dependent RNA helicase and 3' to 5' exoribonuclease activities. Shows a strong preference for pyrimidine over purine residues for its nuclease activity. Acts as a transcriptional coactivator for a number of nuclear receptors including PPARA, PPARG, THRA, THRB and RXRA"
        ],
        "length": 2649,
        "sequence": "MAVWEAEQLGGLQRGDLLTPPAPNGDGRTVPLGQPPGAQLYCPACLVTCHSQEAFENHCASSEHAQMVAFDQAVPWEHRSPPPGLSKFELCPKPDLCEYGDACTKAHSAQELQEWIQRRRAVELRGQAAWQDGLVPYQERLLAEYQRSSSEVLVLTETLDGVRVTCNQPLKYQAQERKTQYSWTFAVHSEEPLLHVALLKQEPGANFSLVAPGLPSGRLYARGERFRLPSSAADFQVGVSVQAASFGTFEQWVVFDFGRRPVLLRKLGLQLGQGRHPEPYSSLALGHPEEMERWHTGNRHVVPAVERTAEQTALMAKYKDPALALEFNRSGLASGPISPTNYRQRMHQFLYEEETAQQQLVAKLTLRGPVFLKTALQTPALNMLFAPPGALYAEVPVPPSLMPDTDQGFLLGRAVSTALVAPVPAPNNAVFEVRLEKRASSEQVLWLLLPARCCLALGLQPEARLVLEVQFQIDPMTFRLWHQAVDTLPEEQLVVPDLPTCALPRPWSVPPLRRGNRKQELAVALIAGWGPGDGKRVPPLLIYGPFGTGKTYTLAMASLEVIRRPQAKVLICTHTNSAADIYIREYFHSHVSGGHPEATPLRVMYADRPPSHTDPVTLQYCCLTDDHQAFRPPTWAELARHRVVVTTTSQARELRVPVGFFSHILIDEAAQMLECEALTPLAYASRGTRLVLAGDHMQVTPRLFSVARARAAEHTLLHRLFLYYQQETHEVARQSRLVFHENYRCTEAIVSFVSRHFYVAKGNPIHARGKVPPHPRHYPLMFCHVAGSPDRDISTTSWLNLAEIAQAVEKVQEAYNTWPSCWGVREQRHICVVSHGAQVGALRQELRRRDLGQVSVGSFEILPGRQFRVVVLSTVHTCQSLLSPGAPAPEFFTDARVLNTVLTRAQSQLVVVGDAVALCSFGACGKLWESFIRECVERHSVCPEGLSMEQVEQGVAQRRRWLPRGTRAGAAGNWEAAPEPAGDPAEEPATVVTATVKAEPGDEALSPASGDITATTAQTEAAAAPAGEAVKEDAAPGAWAVGAAAAAGLESTEPEDAEADFWPWDGELNADDAILRELLDESQKVMVTVGEDGLLDTVARPESPRQARLYENLPPAALRKLLRAEPGRYRHCTFVQETFERASAIPLDDASSGPIPVRGRLDCGMAFTGDEVLVQLLSGDRAPEGRLRGRVLGVLKRRRQELAFVCRMDRWDPRIMVPINGSVTKIFVAELKDPSRVPVYGLRKGRLQRVGFERLTAEARHSRLFWVHIVLWRPGFYYPLGIVREVLPEASTWEQGLRILGLEYSLRVPPSDLAAITKALQKYQTELGRVAGRREDCRAFLTFTVDPQGACNLDDALSVRDLGPRCEVAVHITDVASFVPRDGVLDVEARRQGAAFYAPGQEPVPMLPASLCQDILSLLPGRDRLAISLFLTMEKASGQLKSLHFAPSVVRSDRQLSYEEAEQVIRQHPGAGRELPAHLDSVDACVVAACYFSRLLRRHRLQSDCFYEQPDEDSTLGFRAAHIMVKEYMIQFNRLVAEFLVGSERTRTVTPLRWQPAPHSQQLKALCEKHGERVPLSLHLSHHLRGSGGSTPNTQLHLLASLWKQVQFAARTQDYEQMVDLVTTDDMHPFLAPAGRDLRKALERSAFGRCTWGHRQQGGHYSLQVEWYTWATSPIRRYLDVVLQRQILLALGHGGSAYSARDIDGLCQGFSLQHALAQSYQRRARSLHLAVQLKAQPLDKLGFVVDVEAGSRCFRLQFPSNRETLPDPCPVPYSSLQLAEHPRALAGRPGMQLLWRRRVYSVQGSGPPLPLPGTVLDPHTWAVETALWKQLLVLVELQRWPEAAALIQEKGEASPQRGLVQVQRSRCGHFLEVARELGSGDTLQVQLGASLQHGFLVPNPQLWTVAPGFSLCLEHVERPGDCFLGHVYQAPRDRYRDVDEYACVWEPFCALESATGAVAENDAVTLQHLSVSWDVSRMPQGQLQGAFRLEAAFLEENCVDINLSCCYLCIRLEGLPAPTASPHPGPSSLGPGLSVDPGTYTWVAHGQTEDWDQERRADRQEAPRQVHLFIHHMGMEKVPEEVLRPGTLFTVELLPKQLPDLRKEEAVRGLEEASPLVTSIALGRPVPQPLCRVIPSRFLERQTYDIPGSRHKLNPSQNRAVREALEKPLTVIQGPPGTGKTIVGLHIIFWFHKSNQEQVQPGGSPHGETQLGGPCILYCGPSNKSVDVLAELLLRRMELRPLRVYSEQAEASEFPVPRPGSRKLLRRNPREGRPNQSLRSITLHHRIRQAPNPYSSEIKAFDTRLQSGEPFSREDLVLYKKVLWEARKFELDRHEVILCTCSCAASASLKTLDVRQILVDEAGMATEPETLIPLVRFPQAEKVVLLGDHKQLRPVVKNEWLQNLGLDRSLFERYHEDAHMLDTQYRMHEGICAFPSVAFYKSRLKTWQGLKRLPSVLGHAGKESCPVIFGHVQGHERSLLVSTDEGNENSKANLEEVAEVVRITKQLTLGRTIEPQDVAVLTPYNAQASEISKALRREGITGVAVSSITKSQGSEWRYVLVSTVRTCAKSDLDQRPTKSWLKKFLGFVVDPNQVNVAVTRAQEGLCLIGDHLLLRCCPLWRSLLDFCEAQQSLVPAGQVRVCRRPTMPS",
        "proteome": null,
        "gene": "PRIC285",
        "go_terms": [
            {
                "identifier": "GO:0004386",
                "name": "helicase activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0003723",
                "name": "RNA binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0004540",
                "name": "RNA nuclease activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            }
        ],
        "protein_evidence": 2,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": false,
        "in_bfvd": false,
        "ida_accession": "99eb37237381e5126557e706d2e6ca9272e5bf42",
        "counters": {
            "domain_architectures": 681,
            "entries": 24,
            "isoforms": 0,
            "proteomes": 0,
            "sets": 4,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "ssf": 3,
                "cathgene3d": 1,
                "cdd": 3,
                "pfam": 4,
                "smart": 1,
                "panther": 1,
                "prosite": 1,
                "interpro": 10
            },
            "proteome": 0,
            "taxonomy": 1,
            "similar_proteins": 681
        }
    }
}