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{
    "metadata": {
        "accession": "H9G6N5",
        "id": "H9G6N5_ANOCA",
        "source_organism": {
            "taxId": "28377",
            "scientificName": "Anolis carolinensis",
            "fullName": "Anolis carolinensis (Green anole)"
        },
        "name": "Peptidyl-prolyl cis-trans isomerase E",
        "description": [
            "Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins",
            "Involved in pre-mRNA splicing as component of the spliceosome. Combines RNA-binding and PPIase activities. Binds mRNA and has a preference for single-stranded RNA molecules with poly-A and poly-U stretches, suggesting it binds to the poly(A)-region in the 3'-UTR of mRNA molecules. Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins. Inhibits KMT2A activity; this requires proline isomerase activity"
        ],
        "length": 301,
        "sequence": "MASTKRVLYVGGLAEEVDERVLHAAFIPFGDITDIQIPLDYETEKHRGFAFIEFELAEDAAAAIDNMNESELFGRTIRVNLAKPMRIKEGSSRPVWSDDDWLKKFSGKTLEENVEEEGAEPARSEAQEGEPPAKKSRANPQVYMDIKIGNKPAGRLNILLRSDIVPMTTENFRCLCTHEKGFGFKGSSFHRVIPQFMCQGGDFTNHNGTGGKSIYGKKFDDENFILKHTGPGLLSMANSGPNTNSSQFFLTCDKTDWLDGKHVVFGEVTEGMDVVRKMEAQGTKDGKPKEKIIISDCGEYM",
        "proteome": "UP000001646",
        "gene": "ppie",
        "go_terms": [
            {
                "identifier": "GO:0003676",
                "name": "nucleic acid binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0003723",
                "name": "RNA binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0003755",
                "name": "peptidyl-prolyl cis-trans isomerase activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0000413",
                "name": "protein peptidyl-prolyl isomerization",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            },
            {
                "identifier": "GO:0006457",
                "name": "protein folding",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            }
        ],
        "protein_evidence": 3,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": true,
        "in_bfvd": false,
        "ida_accession": "b9b36787d9478c52c1d0463c9f8611e5e36c3a8b",
        "counters": {
            "domain_architectures": 1756,
            "entries": 23,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 4,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "cathgene3d": 2,
                "ssf": 2,
                "profile": 2,
                "smart": 1,
                "pfam": 2,
                "cdd": 2,
                "pirsf": 1,
                "panther": 1,
                "prints": 1,
                "prosite": 1,
                "interpro": 8
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 1756
        }
    }
}