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{
"metadata": {
"accession": "H9G667",
"id": "H9G667_ANOCA",
"source_organism": {
"taxId": "28377",
"scientificName": "Anolis carolinensis",
"fullName": "Anolis carolinensis (Green anole)"
},
"name": "Peroxisomal coenzyme A diphosphatase NUDT7",
"description": [
"Fatty acyl-coenzyme A (CoA) diphosphatase that hydrolyzes fatty acyl-CoA to yield acyl-4'-phosphopantetheine and adenosine 3',5'-bisphosphate. Cleaves CoA, CoA esters and oxidized CoA with similar efficiencies. Preferentially hydrolyzes medium-chain acyl-CoAs and bile acid-CoAs. Has no activity toward NDP-sugars, CDP-alcohols, (deoxy)nucleoside 5'-triphosphates, nucleoside 5'-di or monophosphates, diadenosine polyphosphates, NAD, NADH, NADP, NADPH or thymidine-5'-monophospho-p-nitrophenyl ester. May be required to eliminate oxidized CoA from peroxisomes, or regulate CoA and acyl-CoA levels in this organelle in response to metabolic demand. Does not play a role in U8 snoRNA decapping activity. Binds U8 snoRNA. Exhibits decapping activity towards dpCoA-capped RNAs in vitro"
],
"length": 239,
"sequence": "MAAAEVSVEDWRRMDVKDKAKLQLKKFDIGERFSHFPGGKASVLLPLMVKDGKLHLLFTVRSMQLRRSPGDVCFPGGRREPTDKDEIDTALRESQEEIGLHPEQAEVICRLVPVLDKTDSLVTPVVAFIEDTFHAHPNPEEVSDTFSMPLEYFIRPSKYNGITVPLNGIPYLMHTFEYDDPEHKRSFKIVGLTAHIAVFLALAVFGEKPTFEVPYDLENLNSSAVNLFLERYKKAKSKL",
"proteome": "UP000001646",
"gene": "NUDT7",
"go_terms": [
{
"identifier": "GO:0010945",
"name": "coenzyme A diphosphatase activity",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0000287",
"name": "magnesium ion binding",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0016818",
"name": "hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0030145",
"name": "manganese ion binding",
"category": {
"code": "F",
"name": "molecular_function"
}
}
],
"protein_evidence": 3,
"source_database": "unreviewed",
"is_fragment": false,
"in_alphafold": true,
"in_bfvd": false,
"ida_accession": "752b3b6d9807717ea1f029db1420a2538cb188ca",
"counters": {
"domain_architectures": 250306,
"entries": 11,
"isoforms": 0,
"proteomes": 1,
"sets": 2,
"structures": 0,
"taxa": 1,
"dbEntries": {
"cathgene3d": 1,
"ssf": 1,
"profile": 1,
"cdd": 1,
"pfam": 1,
"panther": 1,
"prosite": 1,
"interpro": 4
},
"proteome": 1,
"taxonomy": 1,
"similar_proteins": 250306
}
}
}