General Handler

HTTP 200 OK
Allow: GET, HEAD
Content-Type: application/json
InterPro-Version: 108.0
InterPro-Version-Minor: 0
Vary: Accept

{
    "metadata": {
        "accession": "H1VZX9",
        "id": "NIS1_COLHI",
        "source_organism": {
            "taxId": "759273",
            "scientificName": "Colletotrichum higginsianum (strain IMI 349063)",
            "fullName": "Colletotrichum higginsianum (strain IMI 349063) (Crucifer anthracnose fungus)"
        },
        "name": "Necrosis-inducing secreted protein 1",
        "description": [
            "Secreted effector that induces necrotic lesions in Nicotiana benthamiana (PubMed:22352720). Interacts with the host receptor-like kinases (RLKs) BAK1/SERK3 and BKK1/SERK4, inhibits their kinase activity and suppresses INF1-induced pathogen-associated molecular pattern (PAMP)-triggered immunity (PTI) in N.benthamiana (PubMed:30584105). Also interacts with the host receptor-like cytoplasmic kinase (RLCK) BIK1 and inhibits its kinase activity, thereby inhibiting PAMP-induced ROS generation (Probable). In PTI, phosphorylation relaying by RLKs and RLCKs is critical for the initiation of downstream signaling (Probable)"
        ],
        "length": 144,
        "sequence": "MQFRASIAAAAGLFALANARIYGIAFPETVKAGDEVEAVITTENYIQAVQDIAIAFGIATEASAYPETLGNALGSFYLGPEESNTLENITETVTIPAGLAPGQYVVAAGLYSLYGASSSPTLSHYNVTVTVGNVTSETYVGSQR",
        "proteome": "UP000092177",
        "gene": "NIS1",
        "go_terms": null,
        "protein_evidence": 3,
        "source_database": "reviewed",
        "is_fragment": false,
        "in_alphafold": true,
        "in_bfvd": false,
        "ida_accession": "599146f038d77204355a29940b82f9c77368fa06",
        "counters": {
            "domain_architectures": 1666,
            "entries": 2,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 0,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "pfam": 1,
                "interpro": 1
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 1666
        }
    }
}