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InterPro-Version: 108.0
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{
"metadata": {
"accession": "G0ZAK6",
"id": "G0ZAK6_TUPBE",
"source_organism": {
"taxId": "37347",
"scientificName": "Tupaia belangeri",
"fullName": "Tupaia belangeri (Common tree shrew)"
},
"name": "Apolipoprotein A-V",
"description": [
"Minor apolipoprotein mainly associated with HDL and to a lesser extent with VLDL. May also be associated with chylomicrons. Important determinant of plasma triglyceride (TG) levels by both being a potent stimulator of apo-CII lipoprotein lipase (LPL) TG hydrolysis and an inhibitor of the hepatic VLDL-TG production rate (without affecting the VLDL-apoB production rate). Activates poorly lecithin:cholesterol acyltransferase (LCAT) and does not enhance efflux of cholesterol from macrophages. Binds heparin"
],
"length": 369,
"sequence": "MASTAALLTWALALLSAFSATQAQKGFWDYFSQSSGDKGMGEQIRQQKLAREPASLKDSLEQNLNNMDKFLEKLGPLSGQGRETPQFPQDPVGMRQQLQEELEEVRARLEPYMAEAHERVGWNLEELRQQLKPYTVELMEQVALRAQELQEQLRVVGEDTKAHLMGGVDEVRSLLQELQSRVAHHTGRVKELFHPYAERLVSGIGRHVQELHRSVAPHTPASPKRLSRCVQILSRKLTLKAKALHEHIQQNLDQLRKELSVFARANTNPAEEGAGPDPQVLSEEVRQRLQAFRHNTFLQIAAFTHAIDKETEEVQQQLAPPPPGHHAFAPEWQTDSDKALSRLQDRLDDLWEDITYSLHDQGHSHLGDP",
"proteome": null,
"gene": "apoAV",
"go_terms": [
{
"identifier": "GO:0008289",
"name": "lipid binding",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0006869",
"name": "lipid transport",
"category": {
"code": "P",
"name": "biological_process"
}
},
{
"identifier": "GO:0042157",
"name": "lipoprotein metabolic process",
"category": {
"code": "P",
"name": "biological_process"
}
},
{
"identifier": "GO:0005576",
"name": "extracellular region",
"category": {
"code": "C",
"name": "cellular_component"
}
}
],
"protein_evidence": 2,
"source_database": "unreviewed",
"is_fragment": false,
"in_alphafold": true,
"in_bfvd": false,
"ida_accession": "30784adefa18264133d315e6a3bdb7a3148aa7d2",
"counters": {
"domain_architectures": 445,
"entries": 6,
"isoforms": 0,
"proteomes": 0,
"sets": 1,
"structures": 0,
"taxa": 1,
"dbEntries": {
"cathgene3d": 1,
"ssf": 1,
"pfam": 1,
"panther": 1,
"interpro": 2
},
"proteome": 0,
"taxonomy": 1,
"similar_proteins": 445
}
}
}