General Handler

HTTP 200 OK
Allow: GET, HEAD
Content-Type: application/json
InterPro-Version: 108.0
InterPro-Version-Minor: 0
Vary: Accept

{
    "metadata": {
        "accession": "F6UJG8",
        "id": "F6UJG8_HORSE",
        "source_organism": {
            "taxId": "9796",
            "scientificName": "Equus caballus",
            "fullName": "Equus caballus (Horse)"
        },
        "name": "N-lysine methyltransferase SETD6",
        "description": [
            "Protein-lysine N-methyltransferase. Monomethylates 'Lys-310' of the RELA subunit of NF-kappa-B complex, leading to down-regulation of NF-kappa-B transcription factor activity. Monomethylates 'Lys-8' of H2AZ (H2AZK8me1). Required for the maintenance of embryonic stem cell self-renewal. Methylates PAK4"
        ],
        "length": 515,
        "sequence": "MFSEGMTSPGANPHSSSAWRPQPASRGPGAEAGTYAPPRGVAWDAGSVSAGLVTRGAGCPRTMATRAKRRRVAGPAGGGNPDPVAGFLSWCRRVGLELSPKVAVSRQGTVAGYGMVAQESVQPGELLFAVPRAALLSQHTCSISGLLERERGALQSQSGWVPLLLALLHELQAPASPWSPYFALWPELGRLEHPMFWPEEQRRQLLQGTGVPEAVEKDLANIRSEYYSIVLPFMEAHPDLFSPRVRSPELYHQLVALVMAYSFQEPLEEEEDEKEPNSPLMVPAADILNHLANHNANLEYSPNCLRMVATQPIPKGHEIFNTYGQMANWQLIHMYGFVEPYPDNTDDTADIQMVTVREAALQGTKVEAERLLLYERWDFLCKLEMVGEEGAFVIGREEVLTEEELTTTLKVLCMPAEEFREFKDQDGWADDKKEEDSLTITNIPKLKASWRQLLRKSVLLTLQTYATDLKTEQDLLSNKEVYAKLSWREQQALQQSEVCSRWHNSPFREETLRHQ",
        "proteome": "UP000002281",
        "gene": "SETD6",
        "go_terms": [
            {
                "identifier": "GO:0016279",
                "name": "protein-lysine N-methyltransferase activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0018022",
                "name": "peptidyl-lysine methylation",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            },
            {
                "identifier": "GO:0005515",
                "name": "protein binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0018026",
                "name": "peptidyl-lysine monomethylation",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            }
        ],
        "protein_evidence": 3,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": true,
        "in_bfvd": false,
        "ida_accession": "6fbac7c55e0ddca9cc62a2fd9a18d3682d927bf9",
        "counters": {
            "domain_architectures": 6516,
            "entries": 17,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 2,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "cathgene3d": 2,
                "ssf": 2,
                "cdd": 1,
                "profile": 1,
                "pfam": 2,
                "pirsf": 1,
                "panther": 1,
                "interpro": 7
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 6516
        }
    }
}