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{
    "metadata": {
        "accession": "F6U3Z2",
        "id": "F6U3Z2_HORSE",
        "source_organism": {
            "taxId": "9796",
            "scientificName": "Equus caballus",
            "fullName": "Equus caballus (Horse)"
        },
        "name": "Amyloid beta precursor like protein 1",
        "description": [
            "May play a role in postsynaptic function. The C-terminal gamma-secretase processed fragment, ALID1, activates transcription activation through APBB1 (Fe65) binding. Couples to JIP signal transduction through C-terminal binding. May interact with cellular G-protein signaling pathways. Can regulate neurite outgrowth through binding to components of the extracellular matrix such as heparin and collagen I",
            "The gamma-CTF peptide, C30, is a potent enhancer of neuronal apoptosis"
        ],
        "length": 652,
        "sequence": "MGPASPATRGLGRRRGPPPLPLLLPLSLLLLRAQLAVGSLAGGSPGAAEAPGSAQVAGLCGRLTLHRDLRTGRWEPDPQRSRRCLRDPQRVLEYCRQMYPELQIARVEQATQAIPMERWCGGARGGRCAHPHHQVVPFHCLPGEFVSEALLVPEGCRFLHQERMDQCESSTRRHQEAQEACSSQGLILHGSGMLLPCGTDRFRGVEYVCCPPPVTPNPSGTAVGDPSTRSWPPGSRVEGVEDEEEEESFLQPVDDYFVEPPRAEEEEEEKAPPSSSHTPAGVSKVTPTPRPTDGVDVYFGMPGEISEHEGFLRAKMDLEERRMRQINEVMREWAMADNQSKNLPKADRQALNEHFQSILQTLEEQVSGERQRLVETHATRVIALINDQRRAALEGFLAALQGDLPQPERVLLALRRYLRAEQKEQRHTLRHYQHVAAVDPEKAQQMRFQVQTHLQVIEERMNQSLGLLDQNPQLAQELRPQIQELLHSEHLGPNELEAPAPAGSSEDKGELQPLDSKDADTPMALPKGSTEQDAASPGKENMSPLEQYERKVNVSVPRGFPFHSSEIQRDELAPAGTGVSREAVSGLLIMGAGGGSLIVLSLLLLRRKKPYGAISHGVVEVDPMLTLEEQQLRELQRHGYENPTYRFLEERP",
        "proteome": "UP000002281",
        "gene": "APLP1",
        "go_terms": [
            {
                "identifier": "GO:0008201",
                "name": "heparin binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0046914",
                "name": "transition metal ion binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0016020",
                "name": "membrane",
                "category": {
                    "code": "C",
                    "name": "cellular_component"
                }
            }
        ],
        "protein_evidence": 3,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": true,
        "in_bfvd": false,
        "ida_accession": "9de1e266e3e584c01d58ea56cfb911de011004fe",
        "counters": {
            "domain_architectures": 2045,
            "entries": 28,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 0,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "cathgene3d": 3,
                "smart": 1,
                "profile": 2,
                "ssf": 3,
                "pfam": 4,
                "panther": 1,
                "prints": 1,
                "prosite": 2,
                "interpro": 11
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 2045
        }
    }
}