HTTP 200 OK
Allow: GET, HEAD
Content-Type: application/json
InterPro-Version: 108.0
InterPro-Version-Minor: 0
Vary: Accept
{
"metadata": {
"accession": "D2U880",
"id": "D2U880_XANAP",
"source_organism": {
"taxId": "380358",
"scientificName": "Xanthomonas albilineans (strain GPE PC73 / CFBP 7063)",
"fullName": "Xanthomonas albilineans (strain GPE PC73 / CFBP 7063)"
},
"name": "RecBCD enzyme subunit RecD",
"description": [
"A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD"
],
"length": 647,
"sequence": "MNLFDALQRAGTLRTLDLAFAQSLQRLDPTTAPAVLAAAALASLAVASGHAGLDPARANALLDSRDSTAPPLPTTDDWMRALAASRWVAQPVAEDAASADCPLVLERGLLYLRRYREYERRLALGLRRLAAPSPPQGDLAALAPLFAQLFPRAGRQATLDDSFPDRQARAAALALRRALLLVTGGPGTGKTTTIARLLLLRIAQSHTLSMPAPRIALAAPTGRAAERMAESLRAAVAHACADGVDPALAEALPASASTLHRLLGVIRESPRFRHDPDNPLPFEVIVVDEASMVDLPLMCKLVEAVADGAQLILLGDADQLPSVEAGDVLAAILQAAGPGDALQPADAHALRPLLGHSAVATQSGGLIGHRVQLLRSYRQAQDFTLAPLAEAVRTGEADTTMQLLRKGELAGVHFHDGVDDPLVAGGDALFAHWRALGEAANPSEALHAAARLRLLTAVRAGPQGAHTLNARIEQRLAGPTSGHRRLGSATPWFHGRLLLIVENSYRHGLFNGDVGICLRDAQGTLVAWFSGAGDGHVRGFHPAALPAHESAFAMTVHKAQGSEFDTVWLQLPSRDARVISRELVYTGLTRARRALHLAASEPLLRAALARRAARISGLAWRLGGEPALSAHPESLIETGPPVQRGLF",
"proteome": "UP000001890",
"gene": "recD",
"go_terms": [
{
"identifier": "GO:0004386",
"name": "helicase activity",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0008854",
"name": "exodeoxyribonuclease V activity",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0006302",
"name": "double-strand break repair",
"category": {
"code": "P",
"name": "biological_process"
}
},
{
"identifier": "GO:0006310",
"name": "DNA recombination",
"category": {
"code": "P",
"name": "biological_process"
}
},
{
"identifier": "GO:0009338",
"name": "exodeoxyribonuclease V complex",
"category": {
"code": "C",
"name": "cellular_component"
}
}
],
"protein_evidence": 3,
"source_database": "unreviewed",
"is_fragment": false,
"in_alphafold": true,
"in_bfvd": false,
"ida_accession": "0211e1ab09bf686eb96fc60f04f9843e58b1caf5",
"counters": {
"domain_architectures": 5935,
"entries": 17,
"isoforms": 0,
"proteomes": 1,
"sets": 4,
"structures": 0,
"taxa": 1,
"dbEntries": {
"cathgene3d": 2,
"pfam": 3,
"ssf": 1,
"cdd": 2,
"ncbifam": 1,
"hamap": 1,
"panther": 1,
"interpro": 6
},
"proteome": 1,
"taxonomy": 1,
"similar_proteins": 5935
}
}
}