{"metadata":{"accession":"D2U880","id":"D2U880_XANAP","source_organism":{"taxId":"380358","scientificName":"Xanthomonas albilineans (strain GPE PC73 / CFBP 7063)","fullName":"Xanthomonas albilineans (strain GPE PC73 / CFBP 7063)"},"name":"RecBCD enzyme subunit RecD","description":["A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD"],"length":647,"sequence":"MNLFDALQRAGTLRTLDLAFAQSLQRLDPTTAPAVLAAAALASLAVASGHAGLDPARANALLDSRDSTAPPLPTTDDWMRALAASRWVAQPVAEDAASADCPLVLERGLLYLRRYREYERRLALGLRRLAAPSPPQGDLAALAPLFAQLFPRAGRQATLDDSFPDRQARAAALALRRALLLVTGGPGTGKTTTIARLLLLRIAQSHTLSMPAPRIALAAPTGRAAERMAESLRAAVAHACADGVDPALAEALPASASTLHRLLGVIRESPRFRHDPDNPLPFEVIVVDEASMVDLPLMCKLVEAVADGAQLILLGDADQLPSVEAGDVLAAILQAAGPGDALQPADAHALRPLLGHSAVATQSGGLIGHRVQLLRSYRQAQDFTLAPLAEAVRTGEADTTMQLLRKGELAGVHFHDGVDDPLVAGGDALFAHWRALGEAANPSEALHAAARLRLLTAVRAGPQGAHTLNARIEQRLAGPTSGHRRLGSATPWFHGRLLLIVENSYRHGLFNGDVGICLRDAQGTLVAWFSGAGDGHVRGFHPAALPAHESAFAMTVHKAQGSEFDTVWLQLPSRDARVISRELVYTGLTRARRALHLAASEPLLRAALARRAARISGLAWRLGGEPALSAHPESLIETGPPVQRGLF","proteome":"UP000001890","gene":"recD","go_terms":[{"identifier":"GO:0004386","name":"helicase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0008854","name":"exodeoxyribonuclease V activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0006302","name":"double-strand break repair","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0006310","name":"DNA recombination","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0009338","name":"exodeoxyribonuclease V complex","category":{"code":"C","name":"cellular_component"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"0211e1ab09bf686eb96fc60f04f9843e58b1caf5","counters":{"domain_architectures":5935,"entries":17,"isoforms":0,"proteomes":1,"sets":4,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":2,"pfam":3,"ssf":1,"cdd":2,"ncbifam":1,"hamap":1,"panther":1,"interpro":6},"proteome":1,"taxonomy":1,"similar_proteins":5935}}}