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{
    "metadata": {
        "accession": "B6KA42",
        "id": "B6KA42_TOXGV",
        "source_organism": {
            "taxId": "432359",
            "scientificName": "Toxoplasma gondii (strain ATCC 50861 / VEG)",
            "fullName": "Toxoplasma gondii (strain ATCC 50861 / VEG)"
        },
        "name": "Thioredoxin reductase",
        "description": [
            "Catalyzes the transfer of electrons from NADPH to thioredoxins TRX1, TRX2 and TRX3, which in turn act as reductants of disulfide containing proteins. Able to reduce nitroglutathione (GSNO), a compound involved in the transport of nitric oxide (NO); however, TRX1 is more efficient in reducing GSNO. Has no catalytic activity towards oxidized glutathione (GSSG)"
        ],
        "length": 662,
        "sequence": "MSCLSVSAARAYAAAAASRPVSASFLPAFSRLSQCSFLSENCVLRCTSSVYPASHSTHRTNDLQSTLSAVVLPERLPCTPLAHAAAVVAVWNSGSLLVSTPLFSVCRTETISCAPPAQRQQERAFASERKLSVISTNASEMAPTNTNNGAPSCADGEFDYDLAVIGGGSGGLACAKMAAAQGAETVVFDFVQPSTQGSTWGLGGTCVNVGCVPKYLFHHTGLAGANAHWDGPHMGWKGKFEEQVDWGVCVEKVQNYIKSLNFGYRTGLRKAGVTYINAYAKFVSPHELAYTFRGEDKICKARNIVVAVGGRPHIPEEVEGAKELAITSDDIFSLKQAPNKTLCVGASYISLECAGFLRELGFDVTVAVRSILLRGFDRQCAEQVGLCLEEAGVRILRETIPAKMVKQANGKIQVTFQVGKEKKELVEEFDTVLYATGRKADTSNLNLQAAGVETTETGKIVCDGDSHTSAPSVYAIGDAVENFPELTPVAIKAGEILARRLFANSTEHMDFTNIPTTVFTPIEYAHTGYSEEAAEAEFGRDDLEVYLFQFSPLFFSCVHREKAPQARKSPEDVDITPPCLAKLICVKSEDEKVVGIHFVGPNAGELMQGFALAVRLGAKKRDFDKCVGIHPTNAEAFMALTVTKASGEPFVASGGCGGGKCG",
        "proteome": "UP000002226",
        "gene": "BN1205_093780",
        "go_terms": [
            {
                "identifier": "GO:0016491",
                "name": "oxidoreductase activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0050660",
                "name": "flavin adenine dinucleotide binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0045454",
                "name": "cell redox homeostasis",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            },
            {
                "identifier": "GO:0004791",
                "name": "thioredoxin-disulfide reductase (NADPH) activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0016668",
                "name": "oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            }
        ],
        "protein_evidence": 3,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": true,
        "in_bfvd": false,
        "ida_accession": "786e6e0af388e0b289d71a3e92e80414d4c849c2",
        "counters": {
            "domain_architectures": 105347,
            "entries": 17,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 2,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "cathgene3d": 1,
                "ssf": 2,
                "pfam": 2,
                "panther": 1,
                "ncbifam": 1,
                "prosite": 1,
                "prints": 2,
                "interpro": 7
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 105347
        }
    }
}