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{
"metadata": {
"accession": "B2UQG6",
"id": "H0868_AKKM8",
"source_organism": {
"taxId": "349741",
"scientificName": "Akkermansia muciniphila (strain ATCC BAA-835 / DSM 22959 / JCM 33894 / BCRC 81048 / CCUG 64013 / CIP 107961 / Muc)",
"fullName": "Akkermansia muciniphila (strain ATCC BAA-835 / DSM 22959 / JCM 33894 / BCRC 81048 / CCUG 64013 / CIP 107961 / Muc)"
},
"name": "Beta-N-acetylhexosaminidase Amuc_0868",
"description": [
"Potentially capable of cleaving the specific glycoside linkages in the process of mucin degradation in human intestinal tract (Probable). Hydrolyzes chromogenic substrates pNP-beta-GlcNAc with high activity and pNP-beta-GalNAc to a lesser extent, but not pNP-beta-glucose or pNP-beta-galactose (PubMed:32819592). May cleave terminal beta-(1,3)-linked GalNAc residues from extended B antigens (ExtB) on mucin O-linked glycans enabling bacteria to colonize nutritive niches in the host's gut"
],
"length": 549,
"sequence": "MISKCTFSATVFSLFSLCWGAPSSPVLEAPHTIPLPAAMRVQTGESGFSLKNGVRLPEKNPLSRQAERIFRDNGINTALVKNNADIIFTEDASLGREGYRLAVTPDSISIASGSVNGTLYALQSLVQSIAADKNGAPALPRMDVKDQPRFSWRGLMVDSCRHMMPVRDIKKVLDLMERYKFNTLHWHLTDDQGWRLPIAKYPRLTTVGGARAQSPVIGNRNKGDGIPYSGHYTADEIRDVVRYARDRGITVIPEVEMPGHASAAIAAYPELGNTDIPGYEPRVQETWGVHSYTFSPTEKTFRFLEDVIDEICALFPDSPYIHIGGDEAPKNQWKQSPTAQRVMKDNGLANEHELQSYFIRRVEKMINNRGKRLIGWDEIQEGGLSPTATMMVWRSQMPHIAAQALAQGNDIVMTPNSHLYFDYDQGPGKPAAPEYETINNNQLTWQHVYGLEPVPQGTPREREKQVLGCQANIWTEYIPNLPKWEYHVFPRALALAEVAWTPQELKNEKDFRKRLDRQLPFLDARGVNYKRPDNGAPAQPKAVITRERR",
"proteome": "UP000001031",
"gene": "Amuc_0868",
"go_terms": [
{
"identifier": "GO:0004553",
"name": "hydrolase activity, hydrolyzing O-glycosyl compounds",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0005975",
"name": "carbohydrate metabolic process",
"category": {
"code": "P",
"name": "biological_process"
}
},
{
"identifier": "GO:0004563",
"name": "beta-N-acetylhexosaminidase activity",
"category": {
"code": "F",
"name": "molecular_function"
}
}
],
"protein_evidence": 1,
"source_database": "reviewed",
"is_fragment": false,
"in_alphafold": true,
"in_bfvd": false,
"ida_accession": "4175614b488e6f62480b5bc8d42e36992a625e22",
"counters": {
"domain_architectures": 11295,
"entries": 15,
"isoforms": 0,
"proteomes": 1,
"sets": 3,
"structures": 2,
"taxa": 1,
"dbEntries": {
"cathgene3d": 2,
"ssf": 2,
"pfam": 2,
"cdd": 1,
"panther": 1,
"pirsf": 1,
"prints": 1,
"interpro": 5
},
"proteome": 1,
"taxonomy": 1,
"similar_proteins": 11295
}
}
}