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{
    "metadata": {
        "accession": "B0X072",
        "id": "B0X072_CULQU",
        "source_organism": {
            "taxId": "7176",
            "scientificName": "Culex quinquefasciatus",
            "fullName": "Culex quinquefasciatus (Southern house mosquito)"
        },
        "name": "Cystathionine beta-synthase",
        "description": [
            "Hydro-lyase catalyzing the first step of the transsulfuration pathway, where the hydroxyl group of L-serine is displaced by L-homocysteine in a beta-replacement reaction to form L-cystathionine, the precursor of L-cysteine. This catabolic route allows the elimination of L-methionine and the toxic metabolite L-homocysteine. Also involved in the production of hydrogen sulfide, a gasotransmitter with signaling and cytoprotective effects on neurons"
        ],
        "length": 539,
        "sequence": "MSDHRTCPMANGHNGTSSTNGGVDSREQFLAGFKRPDLASRCTWAVGTEEASPHQHRPLVPRPKVLQTILQAVGNTPLVKLNSIPKAANLKCNLYAKCEFMSPGGSVKDRIGLRMIEEAEKKGLLKPGYTIIEPTSGNTGIGLAMGAAVKGYRCLIVMPEKMSNEKVDTLKALGAEVIRTPTEAAFDSPEGLIAVAQRLEKEIPNSIVLNQYTNAGNPLAHYDGTGAEIVDQLEGQVDMVVVGAGTGGTVAGIGRKIKETNPDCVIVGADPEGSILALPDKLNESNVSFYEVEGVGYDFIPTVLDRSVVDRWIKFNDKDALPMARRLIAEEGFLCGGSSGGNVAVALEAAKELKEGQNCVVILPDNIRNYLTKFVSDNWMEARNFKPSVNVHKHKWWNNSLTTLDMTPPPTVGVDVCLQEVINIMQTAHVDHLPVLDGTTVKGMVSLPNLTSKLLNRLAKPSDPVSRAIFKQFVRVDQNDNVGHVSRILEKDAFVLVVKNEKTSDSQLKETVVGVLTQRDLLFYISNAQNVINGDGNSA",
        "proteome": "UP000002320",
        "gene": "6045737",
        "go_terms": [
            {
                "identifier": "GO:0004122",
                "name": "cystathionine beta-synthase activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0019343",
                "name": "L-cysteine biosynthetic process via L-cystathionine",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            },
            {
                "identifier": "GO:0005737",
                "name": "cytoplasm",
                "category": {
                    "code": "C",
                    "name": "cellular_component"
                }
            },
            {
                "identifier": "GO:0006535",
                "name": "L-cysteine biosynthetic process from L-serine",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            }
        ],
        "protein_evidence": 3,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": true,
        "in_bfvd": false,
        "ida_accession": "264b54861be4f332a770a01279b6b265ce4430d9",
        "counters": {
            "domain_architectures": 5489,
            "entries": 21,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 3,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "ssf": 2,
                "cathgene3d": 2,
                "cdd": 2,
                "profile": 1,
                "pfam": 2,
                "smart": 1,
                "ncbifam": 1,
                "panther": 1,
                "prosite": 1,
                "interpro": 8
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 5489
        }
    }
}