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{
    "metadata": {
        "accession": "A8WTJ7",
        "id": "HOT_CAEBR",
        "source_organism": {
            "taxId": "6238",
            "scientificName": "Caenorhabditis briggsae",
            "fullName": "Caenorhabditis briggsae"
        },
        "name": "Hydroxyacid-oxoacid transhydrogenase, mitochondrial",
        "description": [
            "Catalyzes the cofactor-independent reversible oxidation of gamma-hydroxybutyrate (GHB) to succinic semialdehyde (SSA) coupled to reduction of 2-ketoglutarate (2-KG) to D-2-hydroxyglutarate (D-2-HG). L-3-hydroxybutyrate (L-3-OHB) is also a substrate for HOT when using 2-KG as hydrogen acceptor, resulting in the formation of D-2-HG"
        ],
        "length": 465,
        "sequence": "MSASLARGMLHKMGGSCCPHHAPTTNPFRMAKLHGNNKSTDYAFEMVCSTLRFGKGVTLEIGYDVRNLGAKKTLLITDKNVQNTIAFKNAEQALKMVNIEYEIFDDVLIEPSEKSMQKAIAFAKSKPFDSFIAVGGGSVIDTTKAAALYASNPEADFLDFVGPPFGKSLQPKNPMLPLIAVPTTAGTGSETTAAAIMDLPEHKCKTGIRLRCIKPYLAVVDPLNVMSMPRNVAIYSGFDVLCHALESYTALPYDQRSPRPARPEVRPVYQGSNPISDVWSREALRIIGQYFRRSVFDPSDEEARTEMLKASSFAGIGFGNAGVHLCHGLSYPISSQAKGCVAHDYPQDKNLIPHGLSVMTTAVADFEFTTAACPDRHLVAAQTLGADIPNNADNEYISRTLCDQLRGFMKDFGVPNGLKGMGFEYSDIDHLTEAASHSVPNIVISPKSTDRDIISKLYEKSLTVY",
        "proteome": "UP000008549",
        "gene": "hphd-1",
        "go_terms": [
            {
                "identifier": "GO:0004022",
                "name": "alcohol dehydrogenase (NAD+) activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0016491",
                "name": "oxidoreductase activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0046872",
                "name": "metal ion binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            }
        ],
        "protein_evidence": 3,
        "source_database": "reviewed",
        "is_fragment": false,
        "in_alphafold": true,
        "in_bfvd": false,
        "ida_accession": "5b7a857fcd2426c102beb3316b28cb8a761cb0f0",
        "counters": {
            "domain_architectures": 54669,
            "entries": 13,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 3,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "cathgene3d": 2,
                "ssf": 1,
                "cdd": 1,
                "pfam": 2,
                "panther": 1,
                "prosite": 1,
                "interpro": 5
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 54669
        }
    }
}