GET /api/protein/UniProt/A4IFE2/?format=api
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Content-Type: application/json
InterPro-Version: 108.0
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{
"metadata": {
"accession": "A4IFE2",
"id": "A4IFE2_BOVIN",
"source_organism": {
"taxId": "9913",
"scientificName": "Bos taurus",
"fullName": "Bos taurus (Bovine)"
},
"name": "RING finger and CHY zinc finger domain-containing protein 1",
"description": [
"E3 ubiquitin-protein ligase that mediates ubiquitination of target proteins, including p53/TP53, TP73, HDAC1 and CDKN1B. Mediates ubiquitination and degradation of p53/TP53; preferentially acts on tetrameric p53/TP53. Catalyzes monoubiquitinates the translesion DNA polymerase POLH. Involved in the ribosome-associated quality control (RQC) pathway, which mediates the extraction of incompletely synthesized nascent chains from stalled ribosomes: RCHY1 acts downstream of NEMF and recognizes CAT tails associated with stalled nascent chains, leading to their ubiquitination and degradation"
],
"length": 261,
"sequence": "MAFSALEDGARGQAQRRRGCEHYDRGCLLKAPCCDKLYTCRLCHDNNEDHQLDRFKVKEVQCINCEKIQHAQQTCEECSTLFGEYYCSVCHLFDKDKKQYHCENCGICRIGPKEDFFHCLKCNLCLAMNLQGKHKCIENVSRQNCPICLEDIHTSRIAAQVLPCGHLLHRTCYEDMLKEGYRCPLCMRSALDMSRSWRQRDDEVAQTPMPSEYQNMTVDILCNDCNGRSTVQFHILGMKCNICESYNTAQAGKYRISIDQQ",
"proteome": "UP000009136",
"gene": "RCHY1",
"go_terms": [
{
"identifier": "GO:0008270",
"name": "zinc ion binding",
"category": {
"code": "F",
"name": "molecular_function"
}
}
],
"protein_evidence": 2,
"source_database": "unreviewed",
"is_fragment": false,
"in_alphafold": true,
"in_bfvd": false,
"ida_accession": "de01633899f43b66341fedeb4895668a4a4f9bec",
"counters": {
"domain_architectures": 4230,
"entries": 21,
"isoforms": 0,
"proteomes": 1,
"sets": 3,
"structures": 0,
"taxa": 1,
"dbEntries": {
"profile": 3,
"ssf": 3,
"pfam": 3,
"cathgene3d": 2,
"cdd": 1,
"smart": 1,
"panther": 1,
"interpro": 7
},
"proteome": 1,
"taxonomy": 1,
"similar_proteins": 4230
}
}
}