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{
    "metadata": {
        "accession": "A0AAV0A5P6",
        "id": "A0AAV0A5P6_PHORO",
        "source_organism": {
            "taxId": "109678",
            "scientificName": "Phodopus roborovskii",
            "fullName": "Phodopus roborovskii (Roborovski's desert hamster)"
        },
        "name": "Interleukin-1 receptor type 1",
        "description": [
            "Receptor for IL1A, IL1B and IL1RN. After binding to interleukin-1 associates with the coreceptor IL1RAP to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B, MAPK and other pathways. Signaling involves the recruitment of adapter molecules such as TOLLIP, MYD88, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits. Binds ligands with comparable affinity and binding of antagonist IL1RN prevents association with IL1RAP to form a signaling complex. Involved in IL1B-mediated costimulation of IFNG production from T-helper 1 (Th1) cells"
        ],
        "length": 575,
        "sequence": "MENMKVLLRLLCLIVPLLSLETDECKEYLHKIILFSSANEIDIRDCPLTLNEKHGAVIWYKNDSKTPISMELGSRIHQQKERLWFVPAKMEDSGHYYCVARNSTHCLRTKVTVKVLENDPGLCYNAQATFRQRLHIAGDGSLVCPYLDFFKDEKNQLPKVQWYKDCKPLPLDNINFFGAKNKLMVRNVTEEHGGNYTCHVSYTYLGTPYPVTRVIEFITIGSNKNDRPVIVSPRNETLEVAPGSRIQLVCNVTGQATDLVYWKWNGSEIEENDPFLVEDYQLVERPSARRKHTLITTLNISVVQSHFYRHPFTCFVKNSNIIESAHVKLIYPVPDFKNYIIGTFVILTATIICCVFIYKIFKVDIVLWYRDACSDFLPPKASDGKAYDAYILYPKTFREGPSSNLDTFVFKLLPEVLEGQFGYKLFICGRDDYAGEDTIEVTNEYVKKSRRLIIILMRDMGGFSWLSHSSEEQIAIYNALVREGIKVVLLELEKIQDYEKMPESIQFIKRKHGAICWSGDFKERTQHAKTRFWKNVRYHMPAPRQSSLSRHHLLTQDPVLATKEKLQAETHLPIG",
        "proteome": "UP001152836",
        "gene": "Il1r1",
        "go_terms": [
            {
                "identifier": "GO:0007165",
                "name": "signal transduction",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            },
            {
                "identifier": "GO:0004909",
                "name": "interleukin-1, type I, activating receptor activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0004908",
                "name": "interleukin-1 receptor activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            }
        ],
        "protein_evidence": 3,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": true,
        "in_bfvd": false,
        "ida_accession": "76b0a9356838de3843952d07c8936210e8064f8f",
        "counters": {
            "domain_architectures": 31,
            "entries": 26,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 2,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "profile": 2,
                "cathgene3d": 2,
                "smart": 2,
                "pfam": 4,
                "ssf": 2,
                "panther": 1,
                "prints": 3,
                "interpro": 10
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 31
        }
    }
}