GET /api/protein/UniProt/A0AAU8B2Z4/?format=api
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Content-Type: application/json
InterPro-Version: 108.0
InterPro-Version-Minor: 0
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{
"metadata": {
"accession": "A0AAU8B2Z4",
"id": "A0AAU8B2Z4_9VIRU",
"source_organism": {
"taxId": "3145771",
"scientificName": "Dulem virus 60",
"fullName": "Dulem virus 60"
},
"name": "Replication-associated protein G2P",
"description": [
"Isoform G10P protein binds to double-stranded DNA and prevents hydrolysis by nucleases. Additionally, G10P is an inhibitor of DNA replication and may have a role in the transition from semiconservative replicative form DNA replication to single-stranded DNA synthesis in the life cycle",
"Isoform G2P plays an essential role in viral DNA replication. Binds the origin of replication and cleaves the dsDNA replicative form I (RFI) and becomes covalently bound to it via phosphotyrosine bond, generating the dsDNA replicative form II (RFII). In turn, viral DNA replication initiates at the 3'-OH of the cleavage site. After one round of rolling circle synthesis, protein G2P is linked to the newly synthesized ssDNA and joins the ends of the displaced strand to generate a circular single-stranded molecule ready to be packed into a virion"
],
"length": 414,
"sequence": "MIDTLEIHIPVFPAYCRSTAKDCWEIVGDVTDYGLTGNSRYVKKSDDGDNIAYDLYHAYESIPTSHTGIAFKFMHRAYKTMPFVLLNCSIAKILQGHNVYGNLDMISGACEMLGVFKEKFSEFSAYLDFSRAEVVRFDVTLPALTSSLNMAERIRDFLRNVDYGRYRSLSVRNIKEHYNTLYFGSEQSKTGGFKIYCKGIEFNKEMKELEHKALKNCIVSHALLNKVFTPDVREYAQRSIRIEATIKKRAIKEHGLSVNLWDFLVYQYRNPNIYQKLFNLKTGDFIEALKGMYMSFDDDVKLYELLLARLTTITPTGKKSTTKAQNAYNFYKRIKDDGFYEVKRTTEERTFRRNVKSLIDAGLSRAYLQSLAHSEEKPIIRLLNLDMKAENPPSYVHPVSSYFNEFSGYLQRVA",
"proteome": null,
"gene": null,
"go_terms": [
{
"identifier": "GO:0006260",
"name": "DNA replication",
"category": {
"code": "P",
"name": "biological_process"
}
}
],
"protein_evidence": 3,
"source_database": "unreviewed",
"is_fragment": false,
"in_alphafold": false,
"in_bfvd": false,
"ida_accession": "903fef800c9a6aae74a41f11bfafaa62f8643727",
"counters": {
"domain_architectures": 528,
"entries": 6,
"isoforms": 0,
"proteomes": 0,
"sets": 1,
"structures": 0,
"taxa": 1,
"dbEntries": {
"pfam": 2,
"ncbifam": 1,
"interpro": 3
},
"proteome": 0,
"taxonomy": 1,
"similar_proteins": 528
}
}
}