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{
    "metadata": {
        "accession": "A0AAN6MD86",
        "id": "A0AAN6MD86_9PEZI",
        "source_organism": {
            "taxId": "2831512",
            "scientificName": "Staphylotrichum tortipilum",
            "fullName": "Staphylotrichum tortipilum"
        },
        "name": "Thiamine thiazole synthase",
        "description": [
            "Involved in biosynthesis of the thiamine precursor thiazole. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate. The reaction includes an iron-dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate. The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme. May have additional roles in adaptation to various stress conditions and in DNA damage tolerance"
        ],
        "length": 330,
        "sequence": "MAPSAVSPAQQHVQLAVAAKKAQDVVDDTTAAPAPGLTKPLADMMGNWDNFSFAPIRESTVSRAMTSRYFTDLHTHAESDIAIIGAGSCGLSAAYTLSKLRPDLRIALIEAGVAPGGGAWLGGQLFSAMVLRKPADVFLRDVGVPFEDEGDYVVVKHAALFTSAVLERVLRSGNVKMFNATAVEDLITRPCADGEGGIRVAGVVTNWTLVAMHHGDQSCMDPNTINAPVVISTTGHDGPFGAFSVKRLVSMKRLEELEGMRGLDMLRAEDAIVKNTREVVPGLIVGGMELAEIDGANRMGPTFGAMLLSGVKAAEEALRVFDLRKKQNEA",
        "proteome": "UP001303889",
        "gene": "C8A05DRAFT_38423",
        "go_terms": [
            {
                "identifier": "GO:0009228",
                "name": "thiamine biosynthetic process",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            }
        ],
        "protein_evidence": 3,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": true,
        "in_bfvd": false,
        "ida_accession": "571e71cd852e674548876e8def22d01138018e85",
        "counters": {
            "domain_architectures": 3749,
            "entries": 10,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 1,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "ssf": 1,
                "cathgene3d": 2,
                "hamap": 1,
                "panther": 1,
                "ncbifam": 1,
                "pfam": 1,
                "interpro": 3
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 3749
        }
    }
}