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{
    "metadata": {
        "accession": "A0A9V1E618",
        "id": "A0A9V1E618_PANPR",
        "source_organism": {
            "taxId": "9691",
            "scientificName": "Panthera pardus",
            "fullName": "Panthera pardus (Leopard)"
        },
        "name": "Cyclin-T1",
        "description": [
            "Regulatory subunit of the cyclin-dependent kinase pair (CDK9/cyclin-T1) complex, also called positive transcription elongation factor B (P-TEFb), which facilitates the transition from abortive to productive elongation by phosphorylating the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNA Pol II). Required to activate the protein kinase activity of CDK9: acts by mediating formation of liquid-liquid phase separation (LLPS) that enhances binding of P-TEFb to the CTD of RNA Pol II"
        ],
        "length": 726,
        "sequence": "MEGERKNNNKRWYFTREQLENSPSRRFGLDPDKELSSRQQAANLLQDMGQRLNVSQLTINTAIVYMHRFYMIQSFTQFHRNSVAPAALFLAAKVEEQPKKLEHVIKVAHACLHPQESLPDTRSEAYLQQVQDLVILESIILQTLGFELTIDHPHTHVVKCTQLVRASKDLAQTSYFMATNSLHLTTFSLQYTPPVVACVCIHLACKWSNWEIPVSTDGKHWWEYVDATVTLELLDELTHEFLQILEKTPNRLKRIRNWRACQAPKKTKADDRGTDENTSEQTILSMISQSSSDTTIAGLMSMSTSTTSAVPSLPATEESSSNLSNVEMLQGERWLSSQPPFKLEPAQGHRTSENLALIGVDHSLQQDGSNTFISQKQNSKSVPSAKVSLKEYRAKHAEELAAQKRQLENMEANVKSQYAYAAQNLLSHHDSHSSVILKMPVEGSENPERPFLEKPDKAALKMRIPVASGDKAASSKPEEIKMRIKVHAAADKHNSVEDSVTKSREHKDKHKTHPSNHHHHHNHHSHKHSHSQLPAGTGNKRPGDPKHSSQTSTLAHKPYSLSSSFSSSSSTRKRGPSEETGGAVFDHPAKIAKSTKSSSINFPFPPLPTMAQLPGHSSDTSGLPFTQPSCKTRVPHMKLDKGPTGANGHNTTQTIDYQDTVNMLHSLLSAQGVQPTQPPAFEFVHSYGEYLNPRGGGMSSRSGNTDKPRLPPLPSEPPPPLPPLPK",
        "proteome": "UP001165780",
        "gene": "CCNT1",
        "go_terms": [
            {
                "identifier": "GO:0016538",
                "name": "cyclin-dependent protein serine/threonine kinase regulator activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0006357",
                "name": "regulation of transcription by RNA polymerase II",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            }
        ],
        "protein_evidence": 3,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": true,
        "in_bfvd": false,
        "ida_accession": "dece246de228a8112079fa1205668ca2daaefef0",
        "counters": {
            "domain_architectures": 7222,
            "entries": 13,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 2,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "cathgene3d": 1,
                "ssf": 1,
                "cdd": 2,
                "pfam": 2,
                "smart": 1,
                "panther": 1,
                "interpro": 5
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 7222
        }
    }
}