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{
    "metadata": {
        "accession": "A0A9B0WIG5",
        "id": "A0A9B0WIG5_CHRAS",
        "source_organism": {
            "taxId": "185453",
            "scientificName": "Chrysochloris asiatica",
            "fullName": "Chrysochloris asiatica (Cape golden mole)"
        },
        "name": "Cytosolic carboxypeptidase 6",
        "description": [
            "Metallocarboxypeptidase that mediates protein deglutamylation of tubulin and non-tubulin target proteins. Catalyzes the removal of polyglutamate side chains present on the gamma-carboxyl group of glutamate residues within the C-terminal tail of tubulin protein. Specifically cleaves tubulin long-side-chains, while it is not able to remove the branching point glutamate. Also catalyzes the removal of polyglutamate residues from the carboxy-terminus of non-tubulin proteins such as MYLK. Mediates the deglutamylation of nucleotidyltransferase CGAS, leading to CGAS antiviral defense response activation. Involved in KLF4 deglutamylation which promotes KLF4 proteasome-mediated degradation, thereby negatively regulating cell pluripotency maintenance and embryogenesis"
        ],
        "length": 494,
        "sequence": "MAERSQTAPEAGNDMGNDEAIGGNVSKYMVFPTGYCGQPKKGHLVFDACFESGNLGRVDQVSEFEYDLFIRPDTCNPRFRVWFNFTVENVKESQRVIFNIVNFSKTKSLYRDGMAPMVKSTSRPKWQRLPPKNVYYYRCPDHRKNYVMSFAFCFDREDDIYQFAYCYPYTYTRFQHYLDSLQKRNMDYFFREQLGQSVQQRQLDLLTITSPDNLREGTEQKVVFITGRVHPGETPSSFVCQGIIDFLISQHPIARVLREHLVFKIAPMLNPDGVYLGNYRCSLMGFDLNRHWLDPSPWAHPTLHGVKQLIIQMYNDPKTSLEFYIDIHAHSTMMNGFMYGNIFEDEERFQRQAIFPKLLCQNAEDFSFSSTSFNRDAVKAGTGRRFLGGLLDHTSYCYTLEVSFYSYITGGTTVAVPYTEEAYMKLGRNVARTFLDYYRLNPMVEKMAVPMPRLRKEKNPPYKYPLLRGPASNYQDGKGDKKSSVNHKDPSNSF",
        "proteome": "UP000504623",
        "gene": "AGBL4",
        "go_terms": [
            {
                "identifier": "GO:0004181",
                "name": "metallocarboxypeptidase activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0008270",
                "name": "zinc ion binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0006508",
                "name": "proteolysis",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            }
        ],
        "protein_evidence": 3,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": true,
        "in_bfvd": false,
        "ida_accession": "2411e63c3b6002cf2be3e4f9fbada48fb8115c34",
        "counters": {
            "domain_architectures": 8740,
            "entries": 12,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 2,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "cathgene3d": 2,
                "pfam": 2,
                "ssf": 1,
                "profile": 1,
                "smart": 1,
                "cdd": 1,
                "panther": 1,
                "interpro": 3
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 8740
        }
    }
}