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{
    "metadata": {
        "accession": "A0A8U0REV5",
        "id": "A0A8U0REV5_MUSPF",
        "source_organism": {
            "taxId": "9669",
            "scientificName": "Mustela putorius furo",
            "fullName": "Mustela putorius furo (European domestic ferret)"
        },
        "name": "Methylthioribulose-1-phosphate dehydratase",
        "description": [
            "Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway, which plays a key role in cancer, apoptosis, microbial proliferation and inflammation. May inhibit the CASP1-related inflammatory response (pyroptosis), the CASP9-dependent apoptotic pathway and the cytochrome c-dependent and APAF1-mediated cell death"
        ],
        "length": 221,
        "sequence": "MSGCHAPEGDCGSRRCGAQDKEHPRYLIPELCKQFYHLGWVTGTGGGISLKHGNEIYIAPSGVQKERIQPEDMFVCDINEQDISGPPPCKNLKKSQCTPLFMNAYTMRGREFKITHQEMIKGIRKCTSGGYYRYDDMLVVPIIENTPEEKDLKERMARAINEYPDSCAVLVRRHGMYVWGETWEKAKTMCECYDYLFDIAVSMKRVGLDPTQLPVGENGIV",
        "proteome": "UP000000715",
        "gene": "LOC101685991",
        "go_terms": [
            {
                "identifier": "GO:0046872",
                "name": "metal ion binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0019509",
                "name": "L-methionine salvage from methylthioadenosine",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            },
            {
                "identifier": "GO:0005737",
                "name": "cytoplasm",
                "category": {
                    "code": "C",
                    "name": "cellular_component"
                }
            }
        ],
        "protein_evidence": 3,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": true,
        "in_bfvd": false,
        "ida_accession": "88b5949af4437eee368b582b7bd45779a910fc07",
        "counters": {
            "domain_architectures": 64096,
            "entries": 9,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 1,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "cathgene3d": 1,
                "ssf": 1,
                "smart": 1,
                "pfam": 1,
                "hamap": 1,
                "panther": 1,
                "interpro": 3
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 64096
        }
    }
}